UniProt Q30NP1
Polymerase basic protein 2 (Q30NP1)
Polymerase basic protein 2 (UniProt Q30NP1): 10 experimental structures on GenesisL1, 3 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q30NP1
- Protein
- Polymerase basic protein 2
- Experimental structures
- 10
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 4 · 0 records with a druggable one
Structures
10 records of Q30NP1 in the MolNFT archive: 10 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4YD0 | Influenza polymerase basic protein 2 (PB2) bound to an azaindole-tetrazole inhibitor | x-ray diffraction | A | — | — |
| 4YD0 | Influenza polymerase basic protein 2 (PB2) bound to an azaindole- tetrazole inhibitor | x-ray diffraction | A | — | — |
| 5BUH | Influenza PB2 bound to a hydroxymethyl azaindole inhibitor | x-ray diffraction | A | 4V7 | 1 (best 0.41) |
| 5BUH | Influenza PB2 bound to a hydroxymethyl azaindole inhibitor | x-ray diffraction | A | — | — |
| 5F79 | Influenza PB2 bound to an azaindole inhibitor | x-ray diffraction | A | 4V7 | — |
| 5F79 | Influenza PB2 bound to an azaindole inhibitor | x-ray diffraction | A | — | — |
| 5JUN | PB2 bound to an azaindole inhibitor | x-ray diffraction | A | 6NU | 1 (best 0.45) |
| 5JUN | PB2 bound to an azaindole inhibitor | x-ray diffraction | A | 6NU | 1 (best 0.45) |
| 5JUR | PB2 bound to an azaindole inhibitor | x-ray diffraction | A | 6NS | — |
| 5JUR | PB2 bound to an azaindole inhibitor | x-ray diffraction | A | 6NS | 1 (best 0.43) |
Ligands
- 4V7 · N-[(1R,3S)-3-({5-fluoro-2-[5-fluoro-2-(hydroxymethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyrimidin-4-yl}amino)cyclohexyl]pyrrolidine-1-carboxamide · in 2 records
- 6NS · (3~{R})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-4,4-dimethyl-pentanoic acid · in 2 records
- 6NU · (3~{R})-3-[[5-fluoranyl-2-(5-fluoranyl-1~{H}-pyrrolo[2, 3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-3-(1-methylcyclobutyl)propanoic acid · in 2 records
Elsewhere
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