UniProt Q306W4
Aminoglycoside N(3)-acetyltransferase, AAC(3)-IVa (Q306W4)
Aminoglycoside N(3)-acetyltransferase, AAC(3)-IVa (UniProt Q306W4), EC 2.3.1.81: 6 experimental structures on GenesisL1, 5 ligands bound, 32 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q306W4
- Protein
- Aminoglycoside N(3)-acetyltransferase, AAC(3)-IVa
- EC
- 2.3.1.81
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 32 · 3 records with a druggable one
Structures
6 records of Q306W4 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6MN3 | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, apoenzyme | x-ray diffraction | A, B | CL, ZN | 2 (best 0.59) |
| 6MN3 | Crystal structure of aminoglycoside acetyltransferase AAC(3)-iva, apoenzyme | x-ray diffraction | A, B | CL, ZN | — |
| 6MN4 | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, H154A mutant, in complex with… | x-ray diffraction | A, B, C, D, E, F | AM2, ZN, PO4 | 15 (best 0.73) |
| 6MN4 | Crystal structure of aminoglycoside acetyltransferase AAC(3)-iva, H154A mutant, in complex with… | x-ray diffraction | A, B, C, D, E, F | AM2, ZN, PO4 | — |
| 6MN5 | Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, H154A mutant, in complex with… | x-ray diffraction | A, B, C, D, E, F | LLL, ZN | 15 (best 0.69) |
| 6MN5 | Crystal structure of aminoglycoside acetyltransferase AAC(3)-iva, H154A mutant, in complex with… | x-ray diffraction | A, B, C, D, E, F | LLL, ZN | — |
Ligands
- ZN · Zinc ion · in 6 records
- AM2 · Apramycin · in 2 records
- CL · Chloride ion · in 2 records
- LLL · (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-diamino-3-((2R, 3R,6S)-3-amino-6-(aminomethyl)-tetrahydro-2H-pyran-2-yloxy)-2-hydroxycyclohexyloxy)-5-methyl-4-(methylamino)-tetrahydro-2H-pyran-3,5-diol · in 2 records
- PO4 · Phosphate ion · in 2 records
Elsewhere
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