UniProt Q2UVX4
Complement C3 alpha chain (Q2UVX4)
Complement C3 alpha chain (UniProt Q2UVX4): 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2UVX4
- Protein
- Complement C3 alpha chain
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of Q2UVX4 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2B39 | Structure of mammalian C3 with an intact thioester at 3A resolution | x-ray diffraction | A, B | — | — |
| 8CEM | Structure of bovine native C3, re-refinement | x-ray diffraction | E, A, F, B | NAG, BMA | 20 (best 0.85) |
| Q2UVX4 | AlphaFold monomer V2.0 prediction for complement C3 (Q2UVX4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8CEM chain F against the predicted model Q2UVX4: TM-score 0.96, RMSD 1.97 Å
- 8CEM chain E against the predicted model Q2UVX4: TM-score 0.92, RMSD 2.73 Å
- 2B39 chain B against the predicted model Q2UVX4: TM-score 0.67, RMSD 8.02 Å
- 2B39 chain A against the predicted model Q2UVX4: TM-score 0.65, RMSD 8.31 Å
- 8CEM chain B against the predicted model Q2UVX4: TM-score 0.64, RMSD 6.65 Å
- 8CEM chain A against the predicted model Q2UVX4: TM-score 0.63, RMSD 6.66 Å
Elsewhere
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