UniProt Q2TR58
Beta-lactamase (Q2TR58)
Beta-lactamase (UniProt Q2TR58), EC 3.5.2.6: 20 experimental structures on GenesisL1, 5 ligands bound, 53 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q2TR58
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 20
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 53 · 9 records with a druggable one
Structures
20 records of Q2TR58 in the MolNFT archive: 20 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4OH0 | Crystal structure of OXA-58 carbapenemase | x-ray diffraction | A | — | — |
| 4OH0 | Crystal structure of oxa-58 carbapenemase | x-ray diffraction | A | — | — |
| 4Y0O | Crystal structure of OXA-58, a carbapenem hydrolyzing Class D beta-lactamase from Acinetobacter… | x-ray diffraction | A | — | — |
| 4Y0O | Crystal structure of oxa-58, a carbapenem hydrolyzing class D beta- lactamase from acinetobacter… | x-ray diffraction | A | — | — |
| 4Y0T | Crystal structure of apo form of OXA-58, a Carbapenem hydrolyzing Class D beta-lactamase from… | x-ray diffraction | A, B, C, D | — | — |
| 4Y0T | Crystal structure of apo form of oxa-58, a carbapenem hydrolyzing class D beta-lactamase from… | x-ray diffraction | A, B, C, D | — | — |
| 4Y0U | Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed with OXA-58, a Carbapenem… | x-ray diffraction | A, B, C, D | — | — |
| 4Y0U | Crystal structure of 6ALPHA-hydroxymethylpenicillanate complexed with oxa-58, a carbapenem… | x-ray diffraction | A, B, C, D | — | — |
| 5BOH | Crystal Structure of OXA-58 with the Substrate-Binding Cleft in a Closed State | x-ray diffraction | A | — | — |
| 5BOH | Crystal structure of oxa-58 with the substrate-binding cleft in a closed state | x-ray diffraction | A | — | — |
| 7VVI | OXA-58 crystal structure of acylated meropenem complex | x-ray diffraction | A | SO4, MER | 1 (best 0.53) |
| 7VX3 | OXA-58 crystal structure of acylated meropenem complex 2 | x-ray diffraction | A | SO4, MER, DWZ | 1 (best 0.53) |
| 7VX6 | OXA-58 crystal structure of acylated meropenem complex 2 | x-ray diffraction | A | SO4, MER | — |
| 9D78 | Apo-OXA-58 carbapenemase | x-ray diffraction | A, B, C, D | — | 8 (best 0.62) |
| 9D79 | OXA-58-NA-1-157 1.5 min complex | x-ray diffraction | A, B, C, D | Y33 | 8 (best 0.63) |
| 9D7A | OXA-58-NA-1-157 5 min complex | x-ray diffraction | A, B, C, D | Y33 | 7 (best 0.63) |
| 9D7B | OXA-58-NA-1-157 7.5 min complex | x-ray diffraction | A, B, C, D | Y33 | 6 (best 0.65) |
| 9D7C | OXA-58-NA-1-157 10 min complex | x-ray diffraction | A, B, C, D | Y33, CO2 | 9 (best 0.60) |
| 9D7D | OXA-58-NA-1-157 20 min complex | x-ray diffraction | A, B, C, D | Y33, CO2 | 7 (best 0.63) |
| 9D8C | OXA-58-NA-1-157 2.5 hour complex | x-ray diffraction | A, B, C, D | Y33 | 6 (best 0.69) |
Ligands
- Y33 · (5R)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-5-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid · in 6 records
- MER · (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid · in 3 records
- SO4 · Sulfate ion · in 3 records
- CO2 · Carbon dioxide · in 2 records
- DWZ · (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.