UniProt Q2N0S5
Envelope glycoprotein gp160 (Q2N0S5)
Envelope glycoprotein gp160 (UniProt Q2N0S5): 37 experimental structures on GenesisL1, 6 ligands bound, 348 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q2N0S5
- Protein
- Envelope glycoprotein gp160
- Experimental structures
- 37
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 348 · 22 records with a druggable one
Structures
37 records of Q2N0S5 in the MolNFT archive: 37 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4TVP | Crystal Structure of the HIV-1 BG505 SOSIP.664 Env Trimer Ectodomain, Comprising Atomic-Level… | x-ray diffraction | G, B | — | — |
| 4TVP | Crystal structure of the HIV-1 BG505 SOSIP.664 env trimer ectodomain, comprising atomic-level… | x-ray diffraction | G, B | — | — |
| 5U7M | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry… | x-ray diffraction | B, G | NAG, BMA, MAN, SO4, 83G | 13 (best 0.79) |
| 5U7M | Crystal structure of HIV-1 BG505 SOSIP.664 prefusion env trimer bound to small molecule HIV-1 entry… | x-ray diffraction | B, G | NAG, BMA, MAN, SO4, 83G | — |
| 5U7O | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry… | x-ray diffraction | B, G | NAG, MAN, SO4, 83J | 13 (best 0.79) |
| 5U7O | Crystal structure of HIV-1 BG505 SOSIP.664 prefusion env trimer bound to small molecule HIV-1 entry… | x-ray diffraction | B, G | NAG, MAN, SO4, 83J | — |
| 6CDE | Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1… | electron microscopy | C, c, 2 | NAG, MAN | 19 (best 0.83) |
| 6CDI | Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1… | electron microscopy | d, 2, C | NAG, MAN | — |
| 6CE0 | Crystal structure of a HIV-1 clade B tier-3 isolate H078.14 UFO-BG Env trimer in complex with… | x-ray diffraction | B | NAG | 7 (best 0.64) |
| 6CE0 | Crystal structure of a HIV-1 clade B tier-3 isolate H078.14 ufo-bg env trimer in complex with… | x-ray diffraction | B | NAG | — |
| 6CM3 | BG505 SOSIP in complex with sCD4, 17b, 8ANC195 | electron microscopy | D, E, F | NAG, MAN | 20 (best 0.85) |
| 6CM3 | BG505 sosip in complex with SCD4, 17B, 8ANC195 | electron microscopy | D, E, F | NAG, MAN | — |
| 6CRQ | Glutaraldehyde-treated BG505 SOSIP.664 Env in complex with PGV04 Fab | electron microscopy | A, B, F | NAG, MAN | 19 (best 0.84) |
| 6CRQ | Glutaraldehyde-treated BG505 SOSIP.664 env in complex with PGV04 Fab | electron microscopy | A, B, F | NAG, MAN | — |
| 6DFH | BG505 MD64 N332-GT2 SOSIP trimer in complex with germline-reverted BG18 fragment antigen binding | electron microscopy | B, E, F | NAG | 8 (best 0.85) |
| 6DFH | BG505 MD64 N332-GT2 sosip trimer in complex with germline-reverted BG18 fragment antigen binding | electron microscopy | B, E, F | NAG | — |
| 6UDA | Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664 | electron microscopy | Z, F, J | — | 7 (best 0.82) |
| 6UDA | Cryo-EM structure of CH235UCA bound to MAN5-enriched CH505.N279K.G458Y.SOSIP.664 | electron microscopy | Z, F, J | — | — |
| 6VY2 | Cryo-EM structure of M1214_N1 Fab in complex with CH505 TF chimeric SOSIP.664 Env trimer | electron microscopy | B, D, F | NAG | 9 (best 0.80) |
| 6VY2 | Cryo-EM structure of M1214_N1 Fab in complex with CH505 tf chimeric SOSIP.664 env trimer | electron microscopy | B, D, F | NAG | — |
| 7KLC | Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 GP120 core and to 17B Fab | x-ray diffraction | A | NAG, MAN | — |
| 7L8E | BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-1 from animal Rh.33172 (Wk38 time… | electron microscopy | C, D, E, F, A, B | NAG, MAN | 19 (best 0.82) |
| 7L8E | BG505 SOSIP.V5.2(7S) in complex with the polyclonal Fab pabc-1 from animal RH.33172 (WK38 time… | electron microscopy | C, D, E, F, A, B | NAG, MAN | — |
| 7L8F | BG505 SOSIP.v5.2(7S) in complex with the polyclonal Fab pAbC-2 from animal Rh.33172 (Wk38 time… | electron microscopy | C, D, E, F, A, B | NAG, BMA, MAN | 18 (best 0.83) |
| 7L8G | BG505 SOSIP.V5.2(7S) in complex with the polyclonal Fab pabc-3 from animal RH.33172 (WK38 time… | electron microscopy | C, D, E, F, A, B | NAG | — |
| 7UGO | Cryo-EM structure of BG24 inferred germline Fabs with mature CDR3s and 10-1074 Fabs in complex with… | electron microscopy | A, B, C | NAG, MAN, BMA | 20 (best 0.79) |
| 7UGP | Cryo-EM structure of BG24 Fabs with an inferred germline light chain and 10-1074 Fabs in complex… | electron microscopy | A, B, C | NAG, MAN | 20 (best 0.84) |
| 8C8T | cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with bNAbs EPTC112 and 3BNC117 | electron microscopy | A, F, G | NAG | — |
| 8FYI | Structure of HIV-1 BG505 SOSIP-HT1 in complex with one CD4 molecule | electron microscopy | A, B, C | NAG, BMA | 18 (best 0.75) |
| 8FYJ | Structure of HIV-1 BG505 SOSIP-HT2 in complex with two CD4 molecules (class I) | electron microscopy | A, B, C | NAG, BMA, MAN | 18 (best 0.80) |
| 8TKC | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-b.01 FAB | electron microscopy | A, B, C, D, E, F | NAG, MAN | 20 (best 0.83) |
| 8TL2 | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-c.01 FAB | electron microscopy | A, B, C, D, E, F | NAG, MAN | 20 (best 0.82) |
| 8TL4 | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-e.01 FAB | electron microscopy | A, B, C, D, E, F | NAG, MAN | 20 (best 0.83) |
| 8TL5 | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB | electron microscopy | A, B, C, D, E, F | NAG, BMA, MAN | 20 (best 0.84) |
| 8TNU | Cryo-EM structure of TRNM-b*01 Fab in complex with HIV-1 Env trimer BG505.DS SOSIP | electron microscopy | Z, G, E, F, X, Y | NAG, MAN | 14 (best 0.84) |
| 8TO7 | Cryo-EM structure of HERH-b*01 Fab in complex with HIV-1 Env trimer BG505.DS SOSIP | electron microscopy | E, B, D, A, F, C | NAG, MAN | 20 (best 0.84) |
| 8TTW | Cryo-EM structure of BG505 SOSIP.664 HIV-1 Env trimer in complex with temsavir, 8ANC195, and 10-1074 | electron microscopy | B, F, J | NAG | 6 (best 0.84) |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 33 records
- MAN · alpha-D-mannopyranose · in 23 records
- BMA · beta-D-mannopyranose · in 7 records
- SO4 · Sulfate ion · in 4 records
- 83G · 1-[(2R)-4-(benzenecarbonyl)-2-methylpiperazin-1-yl]-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-yl)ethane-1,2-dione · in 2 records
- 83J · 1-[4-(benzenecarbonyl)piperazin-1-yl]-2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]ethane-1,2-dione · in 2 records
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.