UniProt Q2HJH1
Aspartyl aminopeptidase (Q2HJH1)
Aspartyl aminopeptidase (UniProt Q2HJH1), EC 3.4.11.21: 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2HJH1
- Protein
- Aspartyl aminopeptidase
- EC
- 3.4.11.21
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
6 records of Q2HJH1 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3VAR | Crystal structure of DNPEP, ZnZn form | x-ray diffraction | A | — | — |
| 3VAR | Crystal structure of dnpep, znzn form | x-ray diffraction | A | — | — |
| 3VAT | Crystal structure of DNPEP, ZnMg form | x-ray diffraction | A | — | — |
| 3VAT | Crystal structure of dnpep, znmg form | x-ray diffraction | A | — | — |
| 7U5H | Cryo-EM Structure of DNPEP | electron microscopy | A, B, C, D, E, F, G, H, I, J, K, L | ZN | 20 (best 0.77) |
| Q2HJH1 | AlphaFold monomer V2.0 prediction for aspartyl aminopeptidase (Q2HJH1) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 3VAT chain A against the predicted model Q2HJH1: TM-score 1.00, RMSD 0.50 Å
- 3VAT chain A against the predicted model Q2HJH1: TM-score 1.00, RMSD 0.50 Å
- 3VAR chain A against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.53 Å
- 3VAR chain A against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.53 Å
- 7U5H chain D against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.79 Å
- 7U5H chain H against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.79 Å
- 7U5H chain I against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.79 Å
- 7U5H chain A against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.79 Å
- 7U5H chain K against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.79 Å
- 7U5H chain L against the predicted model Q2HJH1: TM-score 0.99, RMSD 0.79 Å
Elsewhere
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