UniProt Q2FWH3
D-alanine--D-alanine ligase (Q2FWH3)
D-alanine--D-alanine ligase (UniProt Q2FWH3), EC 6.3.2.4: 1 experimental structure and 1 predicted model on GenesisL1, 4 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q2FWH3
- Protein
- D-alanine--D-alanine ligase
- EC
- 6.3.2.4
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 7 · 1 record with a druggable one
Structures
2 records of Q2FWH3 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7U9K | Staphylococcus aureus D-alanine-D-alanine ligase in complex with ATP, D-ala-D-ala, Mg2+ and K+ | x-ray diffraction | A, B | K, MG, ADP, ATP | 7 (best 0.83) |
| Q2FWH3 | AlphaFold monomer V2.0 prediction for D-alanine--D-alanine ligase (Q2FWH3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7U9K chain A against the predicted model Q2FWH3: TM-score 0.99, RMSD 0.75 Å
- 7U9K chain B against the predicted model Q2FWH3: TM-score 0.97, RMSD 1.30 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.