UniProt Q24SP6
Methylcorrinoid:tetrahydrofolate methyltransferase (Q24SP6)
Methylcorrinoid:tetrahydrofolate methyltransferase (UniProt Q24SP6), EC 2.1.1.-: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q24SP6
- Protein
- Methylcorrinoid:tetrahydrofolate methyltransferase
- EC
- 2.1.1.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 2 records with a druggable one
Structures
3 records of Q24SP6 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6SK4 | Methyltransferase MtgA from Desulfitobacterium hafniense in complex with methyl-tetrahydrofolate… | x-ray diffraction | A, B, C, D | THH | 11 (best 0.71) |
| 6SK4 | Methyltransferase mtga from desulfitobacterium hafniense in complex with methyl-tetrahydrofolate… | x-ray diffraction | A, B, C, D | — | — |
| Q24SP6 | AlphaFold monomer V2.0 prediction for METHYLCORRINOID:TETRAHYDROFOLATE methyltransferase (Q24SP6) | predicted | A | — | 3 (best 0.56) |
Ligands
- THH · N-[4-({[(6S)-2-amino-4-hydroxy-5-methyl-5,6,7,8-tetrahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid · in 1 record
Experiment against prediction
- 6SK4 chain C against the predicted model Q24SP6: TM-score 0.99, RMSD 0.76 Å
- 6SK4 chain B against the predicted model Q24SP6: TM-score 0.99, RMSD 0.78 Å
- 6SK4 chain D against the predicted model Q24SP6: TM-score 0.99, RMSD 0.79 Å
- 6SK4 chain A against the predicted model Q24SP6: TM-score 0.98, RMSD 0.84 Å
- 6SK4 chain C against the predicted model Q24SP6: TM-score 0.98, RMSD 0.76 Å
- 6SK4 chain B against the predicted model Q24SP6: TM-score 0.98, RMSD 0.78 Å
- 6SK4 chain D against the predicted model Q24SP6: TM-score 0.98, RMSD 0.79 Å
- 6SK4 chain A against the predicted model Q24SP6: TM-score 0.98, RMSD 0.84 Å
Elsewhere
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