UniProt Q24K09
DNA (cytosine-5)-methyltransferase 1 (Q24K09)
DNA (cytosine-5)-methyltransferase 1 (UniProt Q24K09), EC 2.1.1.37: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q24K09
- Protein
- DNA (cytosine-5)-methyltransferase 1
- EC
- 2.1.1.37
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 1 record with a druggable one
Structures
7 records of Q24K09 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PZV | Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin | x-ray diffraction | C, G | ZN | 9 (best 0.79) |
| 6PZV | Crystal structure of bovine DNMT1 rfts domain in complex with H3K9ME3 and ubiquitin | x-ray diffraction | C, G | ZN | — |
| 7LMK | Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me3 | x-ray diffraction | A, B, C, D | ZN | 5 (best 0.39) |
| 7LMK | Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20ME3 | x-ray diffraction | A, B, C, D | ZN | — |
| 7LMM | Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20me2 | x-ray diffraction | A, B, C, D | ZN | 3 (best 0.37) |
| 7LMM | Crystal structure of bovine DNMT1 BAH1 domain in complex with H4K20ME2 | x-ray diffraction | A, B, C, D | ZN | — |
| Q24K09 | AlphaFold monomer V2.0 prediction for DNA (cytosine-5)-methyltransferase 1 (Q24K09) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 6PZV chain C against the predicted model Q24K09: TM-score 0.80, RMSD 3.04 Å
- 6PZV chain C against the predicted model Q24K09: TM-score 0.80, RMSD 3.04 Å
- 6PZV chain G against the predicted model Q24K09: TM-score 0.77, RMSD 3.33 Å
- 6PZV chain G against the predicted model Q24K09: TM-score 0.77, RMSD 3.33 Å
- 7LMM chain B against the predicted model Q24K09: TM-score 0.73, RMSD 1.50 Å
- 7LMM chain B against the predicted model Q24K09: TM-score 0.73, RMSD 1.50 Å
- 7LMK chain B against the predicted model Q24K09: TM-score 0.73, RMSD 1.50 Å
- 7LMK chain B against the predicted model Q24K09: TM-score 0.73, RMSD 1.50 Å
- 7LMK chain C against the predicted model Q24K09: TM-score 0.72, RMSD 1.77 Å
- 7LMK chain C against the predicted model Q24K09: TM-score 0.72, RMSD 1.77 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.