UniProt Q23192
Alpha-tubulin N-acetyltransferase 2 (Q23192)
Alpha-tubulin N-acetyltransferase 2 (UniProt Q23192), EC 2.3.1.108: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 33 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q23192
- Protein
- Alpha-tubulin N-acetyltransferase 2
- EC
- 2.3.1.108
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 33 · 4 records with a druggable one
Structures
5 records of Q23192 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8Y9F | ATAT-2 bound MEC-12/MEC-7 microtubule | electron microscopy | C, I | — | 9 (best 0.85) |
| 8YAJ | ATAT-2 bound MEC-12/MEC-7 microtubule without acetyl-CoA | electron microscopy | C, I | PIN | 7 (best 0.87) |
| 8YAL | ATAT-2 bound K40Q MEC-12/MEC-7 microtubule | electron microscopy | C, I | ACO | 8 (best 0.85) |
| 8YAR | ATAT-2 bound K40R MEC-12/MEC-7 microtubule | electron microscopy | C, I | ACO, G2P | 9 (best 0.84) |
| Q23192 | AlphaFold monomer V2.0 prediction for alpha-tubulin N-acetyltransferase 2 (Q23192) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8YAJ chain C against the predicted model Q23192: TM-score 0.98, RMSD 0.80 Å
- 8YAL chain C against the predicted model Q23192: TM-score 0.97, RMSD 0.85 Å
- 8Y9F chain C against the predicted model Q23192: TM-score 0.97, RMSD 0.88 Å
- 8YAR chain C against the predicted model Q23192: TM-score 0.96, RMSD 1.05 Å
- 8YAJ chain I against the predicted model Q23192: TM-score 0.38, RMSD 2.38 Å
- 8YAL chain I against the predicted model Q23192: TM-score 0.37, RMSD 2.68 Å
- 8YAR chain I against the predicted model Q23192: TM-score 0.37, RMSD 2.46 Å
- 8Y9F chain I against the predicted model Q23192: TM-score 0.36, RMSD 2.36 Å
Elsewhere
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