UniProt Q20BJ8
Cystic fibrosis transmembrane conductance regulator (Q20BJ8)
Cystic fibrosis transmembrane conductance regulator (UniProt Q20BJ8), EC 3.6.3.49, 5.6.1.6: 12 experimental structures on GenesisL1, 4 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q20BJ8
- Protein
- Cystic fibrosis transmembrane conductance regulator
- EC
- 3.6.3.49, 5.6.1.6
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 14 · 3 records with a druggable one
Structures
12 records of Q20BJ8 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GJQ | human NBD1 of CFTR in complex with nanobody T27 | x-ray diffraction | A, C, E, G | ATP | — |
| 6GJQ | Human NBD1 of cftr in complex with nanobody T27 | x-ray diffraction | A, C, E, G | ATP | — |
| 6GJS | Human NBD1 of CFTR in complex with nanobodies D12 and T4 | x-ray diffraction | A | MG, ATP | 6 (best 0.67) |
| 6GJS | Human NBD1 of cftr in complex with nanobodies D12 and T4 | x-ray diffraction | A | MG, ATP | — |
| 6GJU | human NBD1 of CFTR in complex with nanobodies T2a and T4 | x-ray diffraction | A | — | 6 (best 0.68) |
| 6GJU | Human NBD1 of cftr in complex with nanobodies T2A and T4 | x-ray diffraction | A | — | — |
| 6GK4 | Human NBD1 of CFTR in complex with nanobodies D12 and T8 | x-ray diffraction | A, D | MG, ATP | — |
| 6GK4 | Human NBD1 of cftr in complex with nanobodies D12 and T8 | x-ray diffraction | A, D | MG, ATP | — |
| 6GKD | human NBD1 of CFTR in complex with nanobodies D12 and G3a | x-ray diffraction | A, F, I, L, O, R | GLC, Z9N, ATP, MG | — |
| 6GKD | Human NBD1 of cftr in complex with nanobodies D12 and G3A | x-ray diffraction | A, F, I, L, O, R | GLC, Z9N, ATP, MG | — |
| 6ZE1 | human NBD1 of CFTR in complex with nanobody G11a | x-ray diffraction | A | ATP | 2 (best 0.52) |
| 6ZE1 | Human NBD1 of cftr in complex with nanobody G11A | x-ray diffraction | A | ATP | — |
Ligands
Elsewhere
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