UniProt Q1XH17
Tripartite motif-containing protein 72 (Q1XH17)
Tripartite motif-containing protein 72 (UniProt Q1XH17): 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 68 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q1XH17
- Protein
- Tripartite motif-containing protein 72
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 68 · 6 records with a druggable one
Structures
7 records of Q1XH17 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7XV2 | TRIM E3 ubiquitin ligase | x-ray diffraction | A | ZN | 1 (best 0.54) |
| 7XYY | TRIM E3 ubiquitin ligase WT | x-ray diffraction | A, B | ZN | 10 (best 0.87) |
| 7XYZ | TRIM E3 ubiquitin ligase | x-ray diffraction | A, B, C, D | ZN | 20 (best 0.87) |
| 7XZ0 | TRIM E3 ubiquitin ligase | x-ray diffraction | A, B | ZN | 6 (best 0.61) |
| 7XZ1 | TRIM E3 ubiquitin ligase | x-ray diffraction | A, B | ZN | 14 (best 0.79) |
| 7XZ2 | TRIM E3 ubiquitin ligase | x-ray diffraction | A, B, C, D | ZN | 16 (best 0.70) |
| Q1XH17 | AlphaFold monomer V2.0 prediction for tripartite motif-containing protein 72 (Q1XH17) | predicted | A | — | 1 (best 0.43) |
Ligands
- ZN · Zinc ion · in 6 records
Experiment against prediction
- 7XZ1 chain A against the predicted model Q1XH17: TM-score 0.87, RMSD 2.88 Å
- 7XZ0 chain A against the predicted model Q1XH17: TM-score 0.83, RMSD 3.55 Å
- 7XV2 chain A against the predicted model Q1XH17: TM-score 0.81, RMSD 4.12 Å
- 7XZ2 chain B against the predicted model Q1XH17: TM-score 0.78, RMSD 4.41 Å
- 7XYY chain B against the predicted model Q1XH17: TM-score 0.78, RMSD 4.11 Å
- 7XYY chain A against the predicted model Q1XH17: TM-score 0.76, RMSD 4.14 Å
- 7XZ2 chain A against the predicted model Q1XH17: TM-score 0.75, RMSD 4.65 Å
- 7XYZ chain B against the predicted model Q1XH17: TM-score 0.68, RMSD 4.12 Å
- 7XYZ chain A against the predicted model Q1XH17: TM-score 0.67, RMSD 4.35 Å
- 7XYZ chain C against the predicted model Q1XH17: TM-score 0.67, RMSD 4.27 Å
Elsewhere
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