UniProt Q1LX78
Cystic fibrosis transmembrane conductance regulator (Q1LX78)
Cystic fibrosis transmembrane conductance regulator (UniProt Q1LX78), EC 3.6.3.49: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q1LX78
- Protein
- Cystic fibrosis transmembrane conductance regulator
- EC
- 3.6.3.49
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 40 · 2 records with a druggable one
Structures
5 records of Q1LX78 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UAR | Dephosphorylated, ATP-free cystic fibrosis transmembrane conductance regulator (CFTR) from zebrafish | electron microscopy | A | D10 | 20 (best 0.78) |
| 5UAR | Dephosphorylated, ATP-free cystic fibrosis transmembrane conductance regulator (cftr) from zebrafish | electron microscopy | A | D10 | — |
| 5W81 | Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance… | electron microscopy | A | ATP, MG | 20 (best 0.88) |
| 5W81 | Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance… | electron microscopy | A | ATP, MG | — |
| Q1LX78 | AlphaFold monomer V2.0 prediction for cystic fibrosis transmembrane conductance regulator (Q1LX78) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5W81 chain A against the predicted model Q1LX78: TM-score 0.98, RMSD 1.47 Å
- 5W81 chain A against the predicted model Q1LX78: TM-score 0.98, RMSD 1.47 Å
- 5UAR chain A against the predicted model Q1LX78: TM-score 0.79, RMSD 5.58 Å
- 5UAR chain A against the predicted model Q1LX78: TM-score 0.79, RMSD 5.58 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.