UniProt Q18CI5
DNA-directed RNA polymerase subunit alpha (Q18CI5)
DNA-directed RNA polymerase subunit alpha (UniProt Q18CI5), EC 2.7.7.6: 2 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q18CI5
- Protein
- DNA-directed RNA polymerase subunit alpha
- EC
- 2.7.7.6
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 8 · 1 record with a druggable one
Structures
3 records of Q18CI5 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7L7B | Clostridioides difficile RNAP with fidaxomicin | electron microscopy | A, B | — | 7 (best 0.80) |
| 7L7B | Clostridioides difficile rnap with fidaxomicin | electron microscopy | A, B | — | — |
| Q18CI5 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit alpha (Q18CI5) | predicted | A | — | 1 (best 0.45) |
Experiment against prediction
- 7L7B chain A against the predicted model Q18CI5: TM-score 0.94, RMSD 1.50 Å
- 7L7B chain A against the predicted model Q18CI5: TM-score 0.94, RMSD 1.50 Å
- 7L7B chain B against the predicted model Q18CI5: TM-score 0.85, RMSD 2.61 Å
- 7L7B chain B against the predicted model Q18CI5: TM-score 0.85, RMSD 2.61 Å
Elsewhere
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