UniProt Q17RS7
Flap endonuclease GEN homolog 1 (Q17RS7)
Flap endonuclease GEN homolog 1 (UniProt Q17RS7), EC 3.1.-.-: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q17RS7
- Protein
- Flap endonuclease GEN homolog 1
- EC
- 3.1.-.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
3 records of Q17RS7 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5T9J | Crystal Structure of human GEN1 in complex with Holliday junction DNA in the upper interface | x-ray diffraction | A, B | MG | 20 (best 0.72) |
| 5T9J | Crystal structure of human GEN1 in complex with holliday junction DNA in the upper interface | x-ray diffraction | A, B | MG | — |
| Q17RS7 | AlphaFold monomer V2.0 prediction for flap endonuclease gen homolog 1 (Q17RS7) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 2 records
Experiment against prediction
- 5T9J chain B against the predicted model Q17RS7: TM-score 0.97, RMSD 1.38 Å
- 5T9J chain B against the predicted model Q17RS7: TM-score 0.97, RMSD 1.38 Å
- 5T9J chain A against the predicted model Q17RS7: TM-score 0.97, RMSD 1.44 Å
- 5T9J chain A against the predicted model Q17RS7: TM-score 0.97, RMSD 1.44 Å
Elsewhere
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