UniProt Q16719
Kynureninase (Q16719)
Kynureninase (UniProt Q16719), EC 3.7.1.3: 5 experimental structures and 1 predicted model on GenesisL1, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q16719
- Protein
- Kynureninase
- EC
- 3.7.1.3
- Experimental structures
- 5
- Predicted models
- 1
- Pockets
- 5 · 1 record with a druggable one
Structures
6 records of Q16719 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2HZP | Crystal Structure of Homo Sapiens Kynureninase | x-ray diffraction | A | — | — |
| 2HZP | Crystal structure of homo sapiens kynureninase | x-ray diffraction | A | — | — |
| 3E9K | Crystal structure of Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex | x-ray diffraction | A | — | — |
| 3E9K | Crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex | x-ray diffraction | A | — | — |
| 7S3V | Structure of HsKYNase_66, an evolved variant of human kynureninase with greatly increased activity… | x-ray diffraction | A, B | — | 5 (best 0.80) |
| Q16719 | AlphaFold monomer V2.0 prediction for kynureninase (Q16719) | predicted | A | — | — |
Experiment against prediction
- 3E9K chain A against the predicted model Q16719: TM-score 0.99, RMSD 0.96 Å
- 3E9K chain A against the predicted model Q16719: TM-score 0.99, RMSD 0.96 Å
- 2HZP chain A against the predicted model Q16719: TM-score 0.99, RMSD 0.96 Å
- 2HZP chain A against the predicted model Q16719: TM-score 0.99, RMSD 0.96 Å
- 7S3V chain A against the predicted model Q16719: TM-score 0.99, RMSD 1.04 Å
- 7S3V chain B against the predicted model Q16719: TM-score 0.99, RMSD 1.06 Å
Elsewhere
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