UniProt Q15759
Mitogen-activated protein kinase 11 (Q15759)
Mitogen-activated protein kinase 11 (UniProt Q15759), EC 2.7.11.24: 8 experimental structures on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q15759
- Protein
- Mitogen-activated protein kinase 11
- EC
- 2.7.11.24
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
8 records of Q15759 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3GC8 | The structure of p38beta C162S in complex with a dihydroquinazoli | x-ray diffraction | A, B | — | — |
| 3GC8 | The structure of P38BETA C162S in complex with a dihydroquinazolinone | x-ray diffraction | A, B | — | — |
| 3GC9 | The structure of p38beta C119S, C162S in complex with a dihydroquinazoli inhibitor | x-ray diffraction | A, B | — | — |
| 3GC9 | The structure of P38BETA C119S, C162S in complex with a dihydroquinazolinone inhibitor | x-ray diffraction | A, B | — | — |
| 3GP0 | Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib | x-ray diffraction | A | — | — |
| 3GP0 | Crystal structure of human mitogen activated protein kinase 11 (P38 beta) in complex with nilotinib | x-ray diffraction | A | — | — |
| 8YGW | The Crystal Structure of MAPK11 from Biortus | x-ray diffraction | A | B96 | 1 (best 0.75) |
| Q15759 | AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase 11 (Q15759) | — | — | — |
Ligands
- B96 · 1-(5-tert-butyl-2-P-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea · in 1 record
Elsewhere
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