UniProt Q15637
Splicing factor 1 (Q15637)
Splicing factor 1 (UniProt Q15637): 13 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15637
- Protein
- Splicing factor 1
- Experimental structures
- 13
- Predicted models
- 1
- Pockets
- 4 · 0 records with a druggable one
Structures
14 records of Q15637 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1K1G | Structural basis for recognition of the intron branch site RNA by splicing factor 1 | solution nmr | A | — | — |
| 1K1G | Structural basis for recognition of the intron branch site RNA by splicing factor 1 | solution nmr | A | — | — |
| 1OPI | Solution structure of the third RNA recognition motif (rrm) of U2AF65 in complex with an N-terminal… | solution nmr | B | — | — |
| 1OPI | Solution structure of the third RNA recognition motif (rrm) of U2AF65 in complex with an N-terminal… | solution nmr | B | — | — |
| 2M09 | Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3… | solution nmr | A | — | — |
| 2M09 | Structure, phosphorylation and U2AF65 binding of the nterminal domain of splicing factor 1 during 3… | solution nmr | A | — | — |
| 2M0G | Structure, phosphorylation and U2AF65 binding of the Nterminal Domain of splicing factor 1 during 3… | solution nmr | A | — | — |
| 2M0G | Structure, phosphorylation and U2AF65 binding of the nterminal domain of splicing factor 1 during 3… | solution nmr | A | — | — |
| 4FXW | Structure of phosphorylated SF1 complex with U2AF65-UHM domain | x-ray diffraction | B, D | — | — |
| 4FXW | Structure of phosphorylated SF1 complex with U2AF65-uhm domain | x-ray diffraction | B, D | — | — |
| 4FXX | Structure of SF1 coiled-coil domain | x-ray diffraction | A, B, C, D | — | — |
| 4FXX | Structure of SF1 coiled-coil domain | x-ray diffraction | A, B, C, D | — | — |
| 7VPX | The cryo-EM structure of the human pre-A complex | electron microscopy | D | — | — |
| Q15637 | AlphaFold monomer V2.0 prediction for splicing factor 1 (Q15637) | predicted | A | — | 4 (best 0.45) |
Experiment against prediction
- 4FXW chain D against the predicted model Q15637: TM-score 0.88, RMSD 1.95 Å
- 4FXW chain D against the predicted model Q15637: TM-score 0.88, RMSD 1.95 Å
- 4FXW chain B against the predicted model Q15637: TM-score 0.85, RMSD 1.77 Å
- 4FXW chain B against the predicted model Q15637: TM-score 0.85, RMSD 1.77 Å
- 4FXX chain B against the predicted model Q15637: TM-score 0.81, RMSD 2.08 Å
- 4FXX chain B against the predicted model Q15637: TM-score 0.81, RMSD 2.08 Å
- 4FXX chain D against the predicted model Q15637: TM-score 0.77, RMSD 2.41 Å
- 4FXX chain D against the predicted model Q15637: TM-score 0.77, RMSD 2.41 Å
- 4FXX chain A against the predicted model Q15637: TM-score 0.77, RMSD 2.81 Å
- 4FXX chain A against the predicted model Q15637: TM-score 0.77, RMSD 2.81 Å
Elsewhere
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