UniProt Q15257
SERINE/THREONINE-protein phosphatase 2A activator (Q15257)
SERINE/THREONINE-protein phosphatase 2A activator (UniProt Q15257): 12 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15257
- Protein
- SERINE/THREONINE-protein phosphatase 2A activator
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
13 records of Q15257 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2G62 | Crystal structure of human PTPA | x-ray diffraction | A | — | — |
| 2G62 | Crystal structure of human ptpa | x-ray diffraction | A | — | — |
| 2HV6 | Crystal structure of the phosphotyrosyl phosphatase activator | x-ray diffraction | A, B | — | — |
| 2HV6 | Crystal structure of the phosphotyrosyl phosphatase activator | x-ray diffraction | A, B | — | — |
| 2HV7 | Crystal structure of phosphotyrosyl phosphatase activator bound to ATPgammaS | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2HV7 | Crystal structure of phosphotyrosyl phosphatase activator bound to atpgammas | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 2IXM | Structure of human PTPA | x-ray diffraction | A | — | — |
| 2IXM | Structure of human ptpa | x-ray diffraction | A | — | — |
| 4LAC | Crystal Structure of Protein Phosphatase 2A (PP2A) and PP2A phosphatase activator (PTPA) complex… | x-ray diffraction | B | — | — |
| 4LAC | Crystal structure of protein phosphatase 2A (PP2A) and PP2A phosphatase activator (ptpa) complex… | x-ray diffraction | B | — | — |
| 4NY3 | Human PTPA in complex with peptide | x-ray diffraction | A, B | — | — |
| 4NY3 | Human ptpa in complex with peptide | x-ray diffraction | A, B | — | — |
| Q15257 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 2A activator (Q15257) | predicted | A | — | 2 (best 0.60) |
Experiment against prediction
- 4NY3 chain A against the predicted model Q15257: TM-score 1.00, RMSD 0.43 Å
- 4NY3 chain A against the predicted model Q15257: TM-score 1.00, RMSD 0.43 Å
- 4NY3 chain B against the predicted model Q15257: TM-score 1.00, RMSD 0.42 Å
- 4NY3 chain B against the predicted model Q15257: TM-score 1.00, RMSD 0.42 Å
- 2IXM chain A against the predicted model Q15257: TM-score 1.00, RMSD 0.45 Å
- 2IXM chain A against the predicted model Q15257: TM-score 1.00, RMSD 0.45 Å
- 4LAC chain B against the predicted model Q15257: TM-score 0.99, RMSD 0.58 Å
- 4LAC chain B against the predicted model Q15257: TM-score 0.99, RMSD 0.58 Å
- 2HV7 chain A against the predicted model Q15257: TM-score 0.99, RMSD 0.69 Å
- 2HV7 chain A against the predicted model Q15257: TM-score 0.99, RMSD 0.69 Å
Elsewhere
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