UniProt Q15181
Inorganic pyrophosphatase (Q15181)
Inorganic pyrophosphatase (UniProt Q15181), EC 3.6.1.1: 6 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15181
- Protein
- Inorganic pyrophosphatase
- EC
- 3.6.1.1
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 17 · 3 records with a druggable one
Structures
7 records of Q15181 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6C45 | Crystal structure of human inorganic pyrophosphatase in the P212121 space group | x-ray diffraction | A, B, C, D | — | 13 (best 0.69) |
| 6C45 | Crystal structure of human inorganic pyrophosphatase in the P212121 space group | x-ray diffraction | A, B, C, D | — | — |
| 7BTN | Crystal structure of human inorganic pyrophosphatase with metal ions | x-ray diffraction | A | MG | 2 (best 0.56) |
| 7BTN | Crystal structure of human inorganic pyrophosphatase with metal ions | x-ray diffraction | A | MG | — |
| 7CMO | Crystal structure of human inorganic pyrophosphatase | x-ray diffraction | A, B, C, D | — | — |
| 8J7Q | The active site mutant of human inorganic pyrophosphatase | x-ray diffraction | A | — | 2 (best 0.56) |
| Q15181 | AlphaFold monomer V2.0 prediction for inorganic pyrophosphatase (Q15181) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 2 records
Experiment against prediction
- 6C45 chain D against the predicted model Q15181: TM-score 0.99, RMSD 0.58 Å
- 8J7Q chain A against the predicted model Q15181: TM-score 0.99, RMSD 0.57 Å
- 7CMO chain D against the predicted model Q15181: TM-score 0.99, RMSD 0.63 Å
- 7CMO chain B against the predicted model Q15181: TM-score 0.99, RMSD 0.66 Å
- 6C45 chain B against the predicted model Q15181: TM-score 0.99, RMSD 0.68 Å
- 6C45 chain B against the predicted model Q15181: TM-score 0.99, RMSD 0.68 Å
- 6C45 chain C against the predicted model Q15181: TM-score 0.99, RMSD 0.70 Å
- 6C45 chain C against the predicted model Q15181: TM-score 0.99, RMSD 0.70 Å
- 7CMO chain C against the predicted model Q15181: TM-score 0.99, RMSD 0.69 Å
- 7CMO chain A against the predicted model Q15181: TM-score 0.99, RMSD 0.75 Å
Elsewhere
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