UniProt Q15050
Ribosome biogenesis regulatory protein homolog (Q15050)
Ribosome biogenesis regulatory protein homolog (UniProt Q15050): 10 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15050
- Protein
- Ribosome biogenesis regulatory protein homolog
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
11 records of Q15050 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8FKQ | Human nucleolar pre-60S ribosomal subunit (State A2) | electron microscopy | ST | — | — |
| 8FKR | Human nucleolar pre-60S ribosomal subunit (State B1) | electron microscopy | ST | — | — |
| 8FKS | Human nucleolar pre-60S ribosomal subunit (State B2) | electron microscopy | ST | — | — |
| 8FKU | Human nucleolar pre-60S ribosomal subunit (State C2) | electron microscopy | ST | — | — |
| 8FKV | Human nucleolar pre-60S ribosomal subunit (State D1) | electron microscopy | ST | — | — |
| 8FKW | Human nucleolar pre-60S ribosomal subunit (State D2) | electron microscopy | ST | — | — |
| 8FKX | Human nucleolar pre-60S ribosomal subunit (State E) | electron microscopy | ST | — | — |
| 8FL0 | Human nucleolar pre-60S ribosomal subunit (State H) | electron microscopy | ST | — | — |
| 8IR1 | human nuclear pre-60S ribosomal particle - State A | electron microscopy | R | — | 1 (best 0.85) |
| 8IR3 | human nuclear pre-60S ribosomal particle - State B' | electron microscopy | R | — | — |
| Q15050 | AlphaFold monomer V2.0 prediction for ribosome biogenesis regulatory protein homolog (Q15050) | predicted | A | — | 1 (best 0.28) |
Experiment against prediction
- 8IR3 chain R against the predicted model Q15050: TM-score 0.90, RMSD 1.90 Å
- 8FL0 chain ST against the predicted model Q15050: TM-score 0.89, RMSD 2.23 Å
- 8IR1 chain R against the predicted model Q15050: TM-score 0.88, RMSD 2.04 Å
- 8FKS chain ST against the predicted model Q15050: TM-score 0.60, RMSD 1.97 Å
- 8FKQ chain ST against the predicted model Q15050: TM-score 0.54, RMSD 2.18 Å
- 8FKR chain ST against the predicted model Q15050: TM-score 0.54, RMSD 2.15 Å
- 8FKW chain ST against the predicted model Q15050: TM-score 0.37, RMSD 3.08 Å
- 8FKU chain ST against the predicted model Q15050: TM-score 0.37, RMSD 2.99 Å
- 8FKV chain ST against the predicted model Q15050: TM-score 0.35, RMSD 4.77 Å
- 8FKX chain ST against the predicted model Q15050: TM-score 0.32, RMSD 3.80 Å
Elsewhere
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