UniProt Q15024
Exosome complex component RRP42 (Q15024)
Exosome complex component RRP42 (UniProt Q15024): 12 experimental structures and 1 predicted model on GenesisL1, 16 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15024
- Protein
- Exosome complex component RRP42
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 16 · 6 records with a druggable one
Structures
13 records of Q15024 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NN6 | Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4… | x-ray diffraction | E | — | — |
| 2NN6 | Structure of the human RNA exosome composed of RRP41, RRP45, RRP46, RRP43, MTR3, RRP42, CSL4, RRP4… | x-ray diffraction | E | — | — |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | E | — | 3 (best 0.86) |
| 6D6Q | Human nuclear exosome-MTR4 RNA complex - overall reconstruction | electron microscopy | E | — | — |
| 6D6R | Human nuclear exosome-MTR4 RNA complex - composite map after focused reconstruction | electron microscopy | E | — | 3 (best 0.85) |
| 6D6R | Human nuclear exosome-MTR4 RNA complex - composite MAP after focused reconstruction | electron microscopy | E | — | — |
| 6H25 | Human nuclear RNA exosome EXO-10-MPP6 complex | electron microscopy | E | — | — |
| 6H25 | Human nuclear RNA exosome exo-10-MPP6 complex | electron microscopy | E | — | — |
| 9G8M | human 80S ribosome bound by a SKI2-exosome complex | electron microscopy | F | — | 1 (best 0.87) |
| 9G8N | 80S-bound human Ski2-exosome complex | electron microscopy | F | — | 3 (best 0.83) |
| 9G8O | human 40S ribosome bound by a SKI238-exosome complex | electron microscopy | F | — | 2 (best 0.84) |
| 9G8P | 40S-bound human SKI2-exosome complex | electron microscopy | F | — | 4 (best 0.86) |
| Q15024 | AlphaFold monomer V2.0 prediction for exosome complex component RRP42 (Q15024) | predicted | A | — | — |
Experiment against prediction
- 6D6R chain E against the predicted model Q15024: TM-score 0.97, RMSD 1.31 Å
- 6D6R chain E against the predicted model Q15024: TM-score 0.97, RMSD 1.31 Å
- 6D6Q chain E against the predicted model Q15024: TM-score 0.97, RMSD 1.32 Å
- 6D6Q chain E against the predicted model Q15024: TM-score 0.97, RMSD 1.32 Å
- 6H25 chain E against the predicted model Q15024: TM-score 0.96, RMSD 1.44 Å
- 6H25 chain E against the predicted model Q15024: TM-score 0.96, RMSD 1.44 Å
- 9G8N chain F against the predicted model Q15024: TM-score 0.96, RMSD 1.40 Å
- 9G8P chain F against the predicted model Q15024: TM-score 0.96, RMSD 1.44 Å
- 9G8O chain F against the predicted model Q15024: TM-score 0.96, RMSD 1.45 Å
- 9G8M chain F against the predicted model Q15024: TM-score 0.95, RMSD 1.66 Å
Elsewhere
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