UniProt Q15006
ER membrane protein complex subunit 2 (Q15006)
ER membrane protein complex subunit 2 (UniProt Q15006): 12 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15006
- Protein
- ER membrane protein complex subunit 2
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 35 · 6 records with a druggable one
Structures
13 records of Q15006 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WW7 | Structure of the human er membrane protein complex in a lipid nanodisc | electron microscopy | B | — | — |
| 6Y4L | Crystal structure of human ER membrane protein complex subunits EMC2 and EMC9 | x-ray diffraction | A | SO4 | 4 (best 0.69) |
| 6Y4L | Crystal structure of human er membrane protein complex subunits EMC2 and EMC9 | x-ray diffraction | A | SO4 | — |
| 6Z3W | Human ER membrane protein complex | electron microscopy | B | — | — |
| 6Z3W | Human er membrane protein complex | electron microscopy | B | — | — |
| 7ADO | Cryo-EM structure of human er membrane protein complex in lipid nanodiscs | electron microscopy | B | — | — |
| 7ADP | Cryo-EM structure of human er membrane protein complex in gdn detergent | electron microscopy | B | — | — |
| 8EOI | Structure of a human EMC:human Cav1.2 channel complex in GDN detergent | electron microscopy | B | — | 4 (best 0.78) |
| 8J0N | cryo-EM structure of human EMC | electron microscopy | B | — | 8 (best 0.80) |
| 8J0O | cryo-EM structure of human EMC and VDAC | electron microscopy | B | — | 6 (best 0.79) |
| 8S9S | Structure of the human ER membrane protein complex (EMC) in GDN | electron microscopy | 2 | — | 7 (best 0.74) |
| 9C7V | Structure of the human BOS:human EMC complex in GDN | electron microscopy | 2 | — | 6 (best 0.73) |
| Q15006 | AlphaFold monomer V2.0 prediction for er membrane protein complex subunit 2 (Q15006) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 2 records
Experiment against prediction
- 9C7V chain 2 against the predicted model Q15006: TM-score 0.93, RMSD 1.78 Å
- 6WW7 chain B against the predicted model Q15006: TM-score 0.93, RMSD 1.82 Å
- 8S9S chain 2 against the predicted model Q15006: TM-score 0.93, RMSD 1.84 Å
- 7ADO chain B against the predicted model Q15006: TM-score 0.92, RMSD 2.02 Å
- 7ADP chain B against the predicted model Q15006: TM-score 0.91, RMSD 2.04 Å
- 8EOI chain B against the predicted model Q15006: TM-score 0.91, RMSD 2.16 Å
- 8J0N chain B against the predicted model Q15006: TM-score 0.89, RMSD 2.60 Å
- 8J0O chain B against the predicted model Q15006: TM-score 0.89, RMSD 2.59 Å
- 6Z3W chain B against the predicted model Q15006: TM-score 0.86, RMSD 2.53 Å
- 6Z3W chain B against the predicted model Q15006: TM-score 0.86, RMSD 2.53 Å
Elsewhere
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