UniProt Q14JW6
ATP-dependent lipid a-core flippase (Q14JW6)
ATP-dependent lipid a-core flippase (UniProt Q14JW6), EC 3.6.3.-: 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q14JW6
- Protein
- ATP-dependent lipid a-core flippase
- EC
- 3.6.3.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 7 · 2 records with a druggable one
Structures
3 records of Q14JW6 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5DGX | 1.73 Angstrom resolution crystal structure of the ABC-ATPase domain (residues 357-609) of lipid A… | x-ray diffraction | A | ADP | 2 (best 0.62) |
| 5DGX | 1.73 ångström resolution crystal structure of the ABC-ATPase domain (residues 357-609) of lipid a… | x-ray diffraction | A | — | — |
| Q14JW6 | AlphaFold monomer V2.0 prediction for ATP-dependent lipid a-core flippase (Q14JW6) | predicted | A | — | 5 (best 0.69) |
Ligands
- ADP · Adenosine-5'-diphosphate · in 1 record
Experiment against prediction
- 5DGX chain A against the predicted model Q14JW6: TM-score 0.90, RMSD 2.12 Å
- 5DGX chain A against the predicted model Q14JW6: TM-score 0.90, RMSD 2.12 Å
Elsewhere
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