UniProt Q149S1
Tektin-4 (Q149S1)
Tektin-4 (UniProt Q149S1): 4 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q149S1
- Protein
- Tektin-4
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 3 · 2 records with a druggable one
Structures
5 records of Q149S1 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8I7O | In situ structure of axonemal doublet microtubules in mouse sperm with 16-nm repeat | electron microscopy | D2, D3, D4, D7, D8, D9 | — | 1 (best 0.89) |
| 8I7R | In situ structure of axonemal doublet microtubules in mouse sperm with 48-nm repeat | electron microscopy | D1, D2, D3, D4, D5, D6, D7, D8, D9, Da | — | — |
| 8IYJ | Cryo-EM structure of the 48-nm repeat doublet microtubule from mouse sperm | electron microscopy | D0, D1, D2, D3, D4, D5, T0, T1, T2, T3, T4, T5 | — | 1 (best 0.87) |
| 8TO0 | 48-nm repeating structure of doublets from mouse sperm flagella | electron microscopy | Aa, Ab, Ac, Ad, Af, Ag, Ah, Ai | — | — |
| Q149S1 | AlphaFold monomer V2.0 prediction for tektin-4 (Q149S1) | predicted | A | — | 1 (best 0.38) |
Experiment against prediction
- 8TO0 chain Ad against the predicted model Q149S1: TM-score 0.95, RMSD 1.49 Å
- 8IYJ chain D5 against the predicted model Q149S1: TM-score 0.95, RMSD 0.77 Å
- 8TO0 chain Af against the predicted model Q149S1: TM-score 0.95, RMSD 1.54 Å
- 8IYJ chain T4 against the predicted model Q149S1: TM-score 0.93, RMSD 2.11 Å
- 8I7R chain D5 against the predicted model Q149S1: TM-score 0.93, RMSD 1.31 Å
- 8IYJ chain T5 against the predicted model Q149S1: TM-score 0.92, RMSD 1.29 Å
- 8I7R chain D6 against the predicted model Q149S1: TM-score 0.91, RMSD 1.03 Å
- 8I7O chain D7 against the predicted model Q149S1: TM-score 0.91, RMSD 1.32 Å
- 8I7R chain D7 against the predicted model Q149S1: TM-score 0.90, RMSD 2.39 Å
- 8I7O chain D4 against the predicted model Q149S1: TM-score 0.90, RMSD 1.51 Å
Elsewhere
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