UniProt Q149N8
E3 ubiquitin-protein ligase shprh (Q149N8)
E3 ubiquitin-protein ligase shprh (UniProt Q149N8): 4 experimental structures and 1 predicted model on GenesisL1, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q149N8
- Protein
- E3 ubiquitin-protein ligase shprh
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 20 · 1 record with a druggable one
Structures
5 records of Q149N8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M85 | PHD Domain from Human SHPRH | solution nmr | A | — | — |
| 2M85 | Phd domain from human shprh | solution nmr | A | — | — |
| 4QN1 | Crystal Structure of a Functionally Uncharacterized Domain of E3 Ubiquitin Ligase SHPRH | x-ray diffraction | A | — | — |
| 4QN1 | Crystal structure of a functionally uncharacterized domain of E3 ubiquitin ligase shprh | x-ray diffraction | A | — | — |
| Q149N8 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase shprh (Q149N8) | predicted | A | — | 20 (best 0.73) |
Experiment against prediction
- 4QN1 chain A against the predicted model Q149N8: TM-score 0.97, RMSD 1.41 Å
- 4QN1 chain A against the predicted model Q149N8: TM-score 0.97, RMSD 1.41 Å
- 2M85 chain A against the predicted model Q149N8: TM-score 0.60, RMSD 2.95 Å
- 2M85 chain A against the predicted model Q149N8: TM-score 0.60, RMSD 2.95 Å
Elsewhere
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