UniProt Q14995
Nuclear receptor subfamily 1 group D member 2 (Q14995)
Nuclear receptor subfamily 1 group D member 2 (UniProt Q14995): 8 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14995
- Protein
- Nuclear receptor subfamily 1 group D member 2
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 4 · 1 record with a druggable one
Structures
9 records of Q14995 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2V0V | Crystal Structure of Rev-Erb beta | x-ray diffraction | A, B, C, D | — | — |
| 2V0V | Crystal structure of rev-erb beta | x-ray diffraction | A, B, C, D | — | — |
| 2V7C | Crystal Structure of Rev-Erb beta | x-ray diffraction | A, B | — | — |
| 2V7C | Crystal structure of rev-erb beta | x-ray diffraction | A, B | — | — |
| 3CQV | Crystal structure of Reverb beta in complex with heme | x-ray diffraction | A | — | — |
| 3CQV | Crystal structure of reverb beta in complex with heme | x-ray diffraction | A | — | — |
| 4N73 | Crystal structure of the ligand binding domain (LBD) of REV-ERB beta bound to Cobalt Protoporphyrin… | x-ray diffraction | A | — | — |
| 4N73 | Crystal structure of the ligand binding domain (lbd) of rev-erb beta bound to cobalt protoporphyrin… | x-ray diffraction | A | — | — |
| Q14995 | AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 1 group D member 2 (Q14995) | predicted | A | — | 4 (best 0.73) |
Experiment against prediction
- 2V7C chain A against the predicted model Q14995: TM-score 0.91, RMSD 1.92 Å
- 2V7C chain A against the predicted model Q14995: TM-score 0.91, RMSD 1.92 Å
- 2V7C chain B against the predicted model Q14995: TM-score 0.91, RMSD 1.80 Å
- 2V7C chain B against the predicted model Q14995: TM-score 0.91, RMSD 1.80 Å
- 3CQV chain A against the predicted model Q14995: TM-score 0.90, RMSD 1.92 Å
- 3CQV chain A against the predicted model Q14995: TM-score 0.90, RMSD 1.92 Å
- 4N73 chain A against the predicted model Q14995: TM-score 0.89, RMSD 2.09 Å
- 4N73 chain A against the predicted model Q14995: TM-score 0.89, RMSD 2.09 Å
- 2V0V chain C against the predicted model Q14995: TM-score 0.89, RMSD 2.45 Å
- 2V0V chain C against the predicted model Q14995: TM-score 0.89, RMSD 2.45 Å
Elsewhere
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