UniProt Q14839
Q14839
Q14839 (UniProt Q14839): 17 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14839
- Experimental structures
- 17
- Predicted models
- 1
- Ligands
- 3
Structures
18 records of Q14839 in the MolNFT archive: 17 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1MM2 | Solution structure of the 2nd PHD domain from Mi2b | solution nmr | A | — | — |
| 1MM2 | Solution structure of the 2ND phd domain from MI2B | solution nmr | A | — | — |
| 1MM3 | Solution structure of the 2nd PHD domain from Mi2b with C-terminal loop replaced by corresponding… | solution nmr | A | — | — |
| 1MM3 | Solution structure of the 2ND phd domain from MI2B with C-terminal loop replaced by corresponding… | solution nmr | A | — | — |
| 2EE1 | Solution structures of the Chromo domain of human chromodomain helicase-DNA-binding protein 4 | solution nmr | A | — | — |
| 2EE1 | Solution structures of the chromo domain of human chromodomain helicase-DNA-binding protein 4 | solution nmr | A | — | — |
| 2L5U | Structure of the first PHD finger (PHD1) from CHD4 (Mi2b) | solution nmr | A | — | — |
| 2L5U | Structure of the first phd finger (PHD1) from CHD4 (MI2B) | solution nmr | A | — | — |
| 2L75 | Solution structure of CHD4-PHD2 in complex with H3K9me3 | solution nmr | A | — | — |
| 2L75 | Solution structure of CHD4-PHD2 in complex with H3K9ME3 | solution nmr | A | — | — |
| 2N5N | Structure of an N-terminal domain of CHD4 | solution nmr | A | — | — |
| 2N5N | Structure of an N-terminal domain of CHD4 | solution nmr | A | — | — |
| 4O9I | Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding | x-ray diffraction | X | — | — |
| 4O9I | Structure of CHD4 double chromodomains depicts cooperative folding for DNA binding | x-ray diffraction | X | — | — |
| 6Q3M | Structure of CHD4 PHD2 - tandem chromodomains | x-ray diffraction | A, B, C, D | ZN | — |
| 6RYR | Nucleosome-CHD4 complex structure (single CHD4 copy) | electron microscopy | W | ANP, MG, ZN | — |
| 6RYU | Nucleosome-CHD4 complex structure (two CHD4 copies) | electron microscopy | W, V | ANP, MG, ZN | — |
| Q14839 | AlphaFold monomer V2.0 prediction for chromodomain-helicase-DNA- binding protein 4 (Q14839) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6RYR chain W against the predicted model Q14839: TM-score 0.99, RMSD 1.15 Å
- 6RYU chain W against the predicted model Q14839: TM-score 0.98, RMSD 1.26 Å
- 6RYU chain V against the predicted model Q14839: TM-score 0.98, RMSD 1.26 Å
- 6Q3M chain B against the predicted model Q14839: TM-score 0.98, RMSD 0.85 Å
- 6Q3M chain A against the predicted model Q14839: TM-score 0.97, RMSD 0.89 Å
- 6Q3M chain C against the predicted model Q14839: TM-score 0.97, RMSD 1.03 Å
- 6Q3M chain D against the predicted model Q14839: TM-score 0.97, RMSD 1.05 Å
- 4O9I chain X against the predicted model Q14839: TM-score 0.86, RMSD 2.09 Å
- 4O9I chain X against the predicted model Q14839: TM-score 0.86, RMSD 2.09 Å
- 2N5N chain A against the predicted model Q14839: TM-score 0.85, RMSD 1.53 Å
Elsewhere
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