UniProt Q14626
Interleukin-11 receptor subunit alpha (Q14626)
Interleukin-11 receptor subunit alpha (UniProt Q14626): 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14626
- Protein
- Interleukin-11 receptor subunit alpha
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 42 · 4 records with a druggable one
Structures
6 records of Q14626 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6O4P | The crystal structure of the interleukin 11 alpha receptor | x-ray diffraction | A, B | NAG, SO4 | — |
| 8DPS | The structure of the interleukin 11 signalling complex, truncated gp130 | electron microscopy | C, F | NAG | 8 (best 0.68) |
| 8DPT | The structure of the IL-11 signalling complex, with full-length extracellular gp130 | electron microscopy | C, F | NAG | 10 (best 0.76) |
| 8DPU | The crystal structure of the IL-11 signalling complex | x-ray diffraction | C, F, I, L, O, R | NAG | 18 (best 0.78) |
| 8QY4 | Structure of interleukin 11 (gp130 P496L mutant). | electron microscopy | B, E | NAG | 6 (best 0.71) |
| Q14626 | AlphaFold monomer V2.0 prediction for interleukin-11 receptor subunit alpha (Q14626) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6O4P chain A against the predicted model Q14626: TM-score 0.96, RMSD 1.31 Å
- 6O4P chain B against the predicted model Q14626: TM-score 0.95, RMSD 1.49 Å
- 8QY4 chain E against the predicted model Q14626: TM-score 0.95, RMSD 1.44 Å
- 8QY4 chain B against the predicted model Q14626: TM-score 0.95, RMSD 1.44 Å
- 8DPS chain C against the predicted model Q14626: TM-score 0.93, RMSD 1.60 Å
- 8DPS chain F against the predicted model Q14626: TM-score 0.93, RMSD 1.60 Å
- 8DPU chain I against the predicted model Q14626: TM-score 0.93, RMSD 1.94 Å
- 8DPU chain C against the predicted model Q14626: TM-score 0.93, RMSD 1.94 Å
- 8DPU chain L against the predicted model Q14626: TM-score 0.93, RMSD 1.94 Å
- 8DPU chain R against the predicted model Q14626: TM-score 0.93, RMSD 1.94 Å
Elsewhere
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