UniProt Q14241
Elongin-A (Q14241)
Elongin-A (UniProt Q14241): 7 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q14241
- Protein
- Elongin-A
- Experimental structures
- 7
- Predicted models
- 1
- Pockets
- 2 · 2 records with a druggable one
Structures
8 records of Q14241 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HFX | Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast… | x-ray diffraction | A, B, C, D | — | — |
| 4HFX | Crystal structure of a transcription elongation factor B polypeptide 3 from homo sapiens, northeast… | x-ray diffraction | A, B, C, D | — | — |
| 6ZUZ | TFIIS N-terminal domain (TND) from human Elongin-A | solution nmr | A | — | — |
| 6ZUZ | Tfiis N-terminal domain (tnd) from human elongin-a | solution nmr | A | — | — |
| 8OEV | Structure of the mammalian Pol II-SPT6-Elongin complex, lacking ELOA latch (composite structure… | electron microscopy | M | — | 1 (best 0.81) |
| 8OEW | Structure of the mammalian Pol II-Elongin complex, lacking the ELOA latch (composite structure… | electron microscopy | M | — | — |
| 8OF0 | Structure of the mammalian Pol II-SPT6-Elongin complex, Structure 1 | electron microscopy | M | — | 1 (best 0.71) |
| Q14241 | AlphaFold monomer V2.0 prediction for elongin-a (Q14241) | predicted | A | — | — |
Experiment against prediction
- 4HFX chain B against the predicted model Q14241: TM-score 0.94, RMSD 0.75 Å
- 4HFX chain B against the predicted model Q14241: TM-score 0.94, RMSD 0.75 Å
- 4HFX chain A against the predicted model Q14241: TM-score 0.91, RMSD 0.89 Å
- 4HFX chain A against the predicted model Q14241: TM-score 0.91, RMSD 0.89 Å
- 4HFX chain D against the predicted model Q14241: TM-score 0.91, RMSD 0.85 Å
- 4HFX chain D against the predicted model Q14241: TM-score 0.91, RMSD 0.85 Å
- 4HFX chain C against the predicted model Q14241: TM-score 0.87, RMSD 0.94 Å
- 4HFX chain C against the predicted model Q14241: TM-score 0.87, RMSD 0.94 Å
- 6ZUZ chain A against the predicted model Q14241: TM-score 0.84, RMSD 1.84 Å
- 6ZUZ chain A against the predicted model Q14241: TM-score 0.84, RMSD 1.84 Å
Elsewhere
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