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UniProt Q14197

Peptidyl-tRNA hydrolase ICT1, mitochondrial (Q14197)

Peptidyl-tRNA hydrolase ICT1, mitochondrial (UniProt Q14197), EC 3.1.1.29: 30 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q14197
Protein
Peptidyl-tRNA hydrolase ICT1, mitochondrial
EC
3.1.1.29
Experimental structures
30
Predicted models
1
Pockets
1 · 1 record with a druggable one

Structures

31 records of Q14197 in the MolNFT archive: 30 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
3J7YStructure of the large ribosomal subunit from human mitochondriaelectron microscopyp——
3J7YStructure of the large ribosomal subunit from human mitochondriaelectron microscopyp——
3J9MStructure of the human mitochondrial ribosome (class 1)electron microscopyp——
5OOLStructure of a native assembly intermediate of the human mitochondrial ribosome with unfolded…electron microscopyp——
5OOLStructure of a native assembly intermediate of the human mitochondrial ribosome with unfolded…electron microscopyp——
5OOMStructure of a native assembly intermediate of the human mitochondrial ribosome with unfolded…electron microscopyp——
5OOMStructure of a native assembly intermediate of the human mitochondrial ribosome with unfolded…electron microscopyp——
6I9RLarge subunit of the human mitochondrial ribosome in complex with Virginiamycin M and Quinupristinelectron microscopyp——
6NU2Structural insights into unique features of the human mitochondrial ribosome recyclingelectron microscopyp——
6ZS9Human mitochondrial ribosome in complex with ribosome recycling factorelectron microscopyp——
6ZSBHuman mitochondrial ribosome in complex with mRNA and P-site tRNAelectron microscopyp——
6ZSCHuman mitochondrial ribosome in complex with E-site tRNAelectron microscopyp——
7L20Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt.electron microscopyp——
7OF0Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with…electron microscopyp——
7OF0Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with…electron microscopyp——
7OF4Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC…electron microscopyp——
7OF5Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with…electron microscopyp——
7OI6Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1electron microscopyp——
7OI7Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2electron microscopyp——
7OI8Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3Aelectron microscopyp——
7OI9Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3Belectron microscopyp——
7OIACryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3Celectron microscopyp——
7OIBCryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3Delectron microscopyp——
7OICCryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4electron microscopyp——
7OIECryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5Belectron microscopyp——
7PD3Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and…electron microscopyp——
7QH6Cryo-EM structure of the human mtlsu assembly intermediate upon MRM2 depletion - class 1electron microscopyp——
8K2ACryo-EM structure of the human 55S mitoribosome with Tigecyclineelectron microscopyL7——
8OIR55S human mitochondrial ribosome with mtRF1 and P-site tRNAelectron microscopyBf——
8OIT39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNAelectron microscopyBf—1 (best 0.84)
Q14197AlphaFold monomer V2.0 prediction for peptidyl-tRNA hydrolase ICT1, mitochondrial (Q14197)predictedA——

Experiment against prediction

Elsewhere

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