UniProt Q13946
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Q13946)
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (UniProt Q13946), EC 3.1.4.53: 9 experimental structures on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q13946
- Protein
- High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A
- EC
- 3.1.4.53
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 2 · 1 record with a druggable one
Structures
9 records of Q13946 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ZKL | Multiple Determinants for Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases | x-ray diffraction | A | — | — |
| 1ZKL | Multiple determinants for inhibitor selectivity of cyclic nucleotide phosphodiesterases | x-ray diffraction | A | — | — |
| 3G3N | PDE7A catalytic domain in complex with 3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-one | x-ray diffraction | A | — | — |
| 3G3N | PDE7A catalytic domain in complex with 3-(2,6- difluorophenyl)-2-(METHYLTHIO)QUINAZOLIN-4(3H)-one | x-ray diffraction | A | — | — |
| 4PM0 | PDE7A catalytic domain in complex with 2-(Cyclopentylamino)thieno[3,2-d]pyrimidin-4(3H)-one… | x-ray diffraction | A | — | — |
| 4PM0 | PDE7A catalytic domain in complex with 2-(CYCLOPENTYLAMINO)THIENO[3,2- D]PYRIMIDIN-4(3H)-one… | x-ray diffraction | A | — | — |
| 4Y2B | Co-crystal structure of 3-ethyl-2-(isopropylamino)-7-(pyridin-3-yl)thieno[3,2-d]pyrimidin-4(3H)-one… | x-ray diffraction | A | ZN, MG, EPK | 2 (best 0.74) |
| 4Y2B | Co-crystal structure of 3-ethyl-2-(isopropylamino)-7-(pyridin-3-yl)… | x-ray diffraction | A | — | — |
| Q13946 | AlphaFold monomer V2.0 prediction for high affinity camp-specific 3',5'-cyclic phosphodiesterase 7A… | — | — | — |
Ligands
Elsewhere
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