UniProt Q13698
Voltage-dependent L-type calcium channel subunit alpha-1S (Q13698)
Voltage-dependent L-type calcium channel subunit alpha-1S (UniProt Q13698): 4 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13698
- Protein
- Voltage-dependent L-type calcium channel subunit alpha-1S
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of Q13698 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2VAY | Calmodulin complexed with CaV1.1 IQ peptide | x-ray diffraction | B | — | — |
| 2VAY | Calmodulin complexed with CAV1.1 iq peptide | x-ray diffraction | B | — | — |
| 6B27 | Crystal structure of human STAC2 Tandem SH3 Domains (296-411) in complex with a CaV1.1 II-III loop… | x-ray diffraction | G, H, I, J, K, L | — | 1 (best 0.31) |
| 6B27 | Crystal structure of human STAC2 tandem SH3 domains (296-411) in complex with a CAV1.1 II-III loop… | x-ray diffraction | G, H, I, J, K, L | — | — |
| Q13698 | AlphaFold monomer V2.0 prediction for voltage-dependent L-type calcium channel subunit alpha-1S… | predicted | A | — | — |
Experiment against prediction
- 2VAY chain B against the predicted model Q13698: TM-score 0.74, RMSD 0.34 Å
- 2VAY chain B against the predicted model Q13698: TM-score 0.74, RMSD 0.34 Å
- 6B27 chain J against the predicted model Q13698: TM-score 0.53, RMSD 0.94 Å
- 6B27 chain J against the predicted model Q13698: TM-score 0.53, RMSD 0.94 Å
- 6B27 chain L against the predicted model Q13698: TM-score 0.51, RMSD 0.95 Å
- 6B27 chain L against the predicted model Q13698: TM-score 0.51, RMSD 0.95 Å
- 6B27 chain K against the predicted model Q13698: TM-score 0.49, RMSD 0.76 Å
- 6B27 chain K against the predicted model Q13698: TM-score 0.49, RMSD 0.76 Å
- 6B27 chain G against the predicted model Q13698: TM-score 0.43, RMSD 0.81 Å
- 6B27 chain G against the predicted model Q13698: TM-score 0.43, RMSD 0.81 Å
Elsewhere
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