UniProt Q13620
Cullin-4B (Q13620)
Cullin-4B (UniProt Q13620): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 13 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13620
- Protein
- Cullin-4B
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 13 · 1 record with a druggable one
Structures
10 records of Q13620 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DO7 | Solution structure of the winged helix-turn-helix motif of human CUL-4B | solution nmr | A | — | — |
| 2DO7 | Solution structure of the winged helix-turn-helix motif of human cul- 4B | solution nmr | A | — | — |
| 4A0C | Structure of the CAND1-CUL4B-RBX1 complex | x-ray diffraction | C, E | — | — |
| 4A0C | Structure of the CAND1-CUL4B-RBX1 complex | x-ray diffraction | C, E | — | — |
| 4A0L | Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex | x-ray diffraction | E, H | — | — |
| 4A0L | Structure of DDB1-DDB2-CUL4B-RBX1 bound to a 12 bp abasic site containing DNA-duplex | x-ray diffraction | E, H | — | — |
| 4A64 | Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution | x-ray diffraction | A, B, C, D | — | — |
| 4A64 | Crystal structure of the N-terminal domain of human CUL4B at 2.57A resolution | x-ray diffraction | A, B, C, D | — | — |
| 8EI1 | Crystal structure of the N-terminal domain of CUL4B in complex with H316, a Helicon Polypeptide | x-ray diffraction | A, B, C, D | WHL | 13 (best 0.82) |
| Q13620 | AlphaFold monomer V2.0 prediction for cullin-4B (Q13620) | predicted | A | — | — |
Ligands
- WHL · N,N'-(1,4-phenylene)diacetamide · in 1 record
Experiment against prediction
- 4A64 chain D against the predicted model Q13620: TM-score 0.99, RMSD 0.78 Å
- 4A64 chain D against the predicted model Q13620: TM-score 0.99, RMSD 0.78 Å
- 4A64 chain C against the predicted model Q13620: TM-score 0.98, RMSD 1.28 Å
- 4A64 chain C against the predicted model Q13620: TM-score 0.98, RMSD 1.28 Å
- 8EI1 chain C against the predicted model Q13620: TM-score 0.97, RMSD 1.29 Å
- 8EI1 chain D against the predicted model Q13620: TM-score 0.97, RMSD 1.44 Å
- 8EI1 chain A against the predicted model Q13620: TM-score 0.97, RMSD 1.45 Å
- 4A64 chain B against the predicted model Q13620: TM-score 0.96, RMSD 1.47 Å
- 4A64 chain B against the predicted model Q13620: TM-score 0.96, RMSD 1.47 Å
- 8EI1 chain B against the predicted model Q13620: TM-score 0.96, RMSD 1.53 Å
Elsewhere
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