UniProt Q13470
Non-receptor tyrosine-protein kinase TNK1 (Q13470)
Non-receptor tyrosine-protein kinase TNK1 (UniProt Q13470), EC 2.7.10.2: 6 experimental structures on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q13470
- Protein
- Non-receptor tyrosine-protein kinase TNK1
- EC
- 2.7.10.2
- Experimental structures
- 6
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 2 · 0 records with a druggable one
Structures
6 records of Q13470 in the MolNFT archive: 6 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7TCY | The ubiquitin-associated domain of human thirty-eight negative kinase I | x-ray diffraction | A, B | PO4, MG, CL | 1 (best 0.40) |
| 7TDY | The ubiquitin-associated domain of human thirty-eight negative kinase 1, flexibly fused to the 1TEL… | x-ray diffraction | A | — | — |
| 7U4W | The ubiquitin-associated domain of human thirty-eight negative kinase-1 flexibly fused to the 1TEL… | x-ray diffraction | A | — | — |
| 7U4Z | The ubiquitin-associated domain of human thirty-eight negative kinase-1 flexibly fused to the 1TEL… | x-ray diffraction | A | — | — |
| 9CPL | The ubiquitin-associated domain of human thirty-eight negative kinase 1, fused to the 2TEL… | x-ray diffraction | A | — | 1 (best 0.46) |
| Q13470 | AlphaFold monomer V2.0 prediction for non-receptor tyrosine-protein kinase TNK1 (Q13470) | — | — | — |
Ligands
Experiment against prediction
- 7U4W chain A against the predicted model P41212: TM-score 0.51, RMSD 2.95 Å
- 7U4Z chain A against the predicted model P41212: TM-score 0.49, RMSD 2.66 Å
- 7TDY chain A against the predicted model P41212: TM-score 0.48, RMSD 2.49 Å
- 9CPL chain A against the predicted model P41212: TM-score 0.42, RMSD 2.65 Å
Elsewhere
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