UniProt Q13467
Frizzled-5 (Q13467)
Frizzled-5 (UniProt Q13467): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13467
- Protein
- Frizzled-5
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 10 · 0 records with a druggable one
Structures
7 records of Q13467 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5URY | Crystal structure of Frizzled 5 CRD in complex with PAM | x-ray diffraction | A, B | NAG, FUC, PAM | 5 (best 0.41) |
| 5URY | Crystal structure of frizzled 5 crd in complex with pam | x-ray diffraction | A, B | NAG, FUC, PAM | — |
| 5URZ | Crystal structure of Frizzled 5 CRD in complex with BOG | x-ray diffraction | A, B | NAG, FUC | 5 (best 0.41) |
| 5URZ | Crystal structure of frizzled 5 crd in complex with bog | x-ray diffraction | A, B | NAG, FUC | — |
| 6O39 | Crystal structure of frizzled 5 crd in complex with F2.I Fab | x-ray diffraction | C | NAG | — |
| 6WW2 | Structure of human FRIZZLED5 by fiducial-assisted cryo-EM | electron microscopy | R | — | — |
| Q13467 | AlphaFold monomer V2.0 prediction for frizzled-5 (Q13467) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5URY chain A against the predicted model Q13467: TM-score 0.99, RMSD 0.49 Å
- 5URY chain A against the predicted model Q13467: TM-score 0.99, RMSD 0.49 Å
- 5URZ chain A against the predicted model Q13467: TM-score 0.98, RMSD 0.51 Å
- 5URZ chain A against the predicted model Q13467: TM-score 0.98, RMSD 0.51 Å
- 6O39 chain C against the predicted model Q13467: TM-score 0.98, RMSD 0.59 Å
- 5URY chain B against the predicted model Q13467: TM-score 0.97, RMSD 0.70 Å
- 5URY chain B against the predicted model Q13467: TM-score 0.97, RMSD 0.70 Å
- 5URZ chain B against the predicted model Q13467: TM-score 0.97, RMSD 0.71 Å
- 5URZ chain B against the predicted model Q13467: TM-score 0.97, RMSD 0.71 Å
- 6WW2 chain R against the predicted model Q13467: TM-score 0.75, RMSD 1.69 Å
Elsewhere
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