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UniProt Q13435

Splicing factor 3B subunit 2 (Q13435)

Splicing factor 3B subunit 2 (UniProt Q13435): 43 experimental structures on GenesisL1, 40 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q13435
Protein
Splicing factor 3B subunit 2
Experimental structures
43
Predicted models
0
Pockets
40 · 15 records with a druggable one

Structures

43 records of Q13435 in the MolNFT archive: 43 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
2DO5Solution structure of the SAP domain of human splicing factor 3B subunit 2solution nmrA——
2DO5Solution structure of the sap domain of human splicing factor 3B subunit 2solution nmrA——
5Z56cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom.electron microscopy2——
5Z58Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström.electron microscopy2——
6AH0The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)electron microscopy2——
6AH0The cryo-EM structure of the precusor of human pre-catalytic spliceosome (pre-B complex)electron microscopy2——
6AHDThe Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolutionelectron microscopy2——
6FF4human Bact spliceosome core structureelectron microscopy8—3 (best 0.88)
6FF4Human bact spliceosome core structureelectron microscopy8——
6FF7human Bact spliceosome core structureelectron microscopy8—2 (best 0.86)
6FF7Human bact spliceosome core structureelectron microscopy8——
6QX9Structure of a human fully-assembled precatalytic spliceosome (pre-B complex).electron microscopyB2——
6Y505'domain of human 17S U2 snRNPelectron microscopy8—3 (best 0.85)
6Y505'DOMAIN of human 17S U2 snrnpelectron microscopy8——
6Y53human 17S U2 snRNP low resolution partelectron microscopy8—1 (best 0.71)
6Y53Human 17S U2 snrnp low resolution partelectron microscopy8——
6Y5QHuman 17S U2 snrnpelectron microscopy8——
7ABGHuman pre-Bact-1 spliceosomeelectron microscopyT—1 (best 0.82)
7ABHHuman pre-bact-2 spliceosome (SF3B/U2 snrnp portion)electron microscopyT——
7ABIHuman pre-bact-2 spliceosomeelectron microscopyT——
7DVQCryo-EM Structure of the Activated Human Minor Spliceosome (minor Bact Complex)electron microscopy2—2 (best 0.84)
7DVQCryo-EM structure of the activated human minor spliceosome (minor bact complex)electron microscopy2——
7EVOThe cryo-EM structure of the human 17S U2 snRNPelectron microscopy2——
7EVOThe cryo-EM structure of the human 17S U2 snrnpelectron microscopy2——
7ONBStructure of the U2 5' module of the A3'-ssa complexelectron microscopyI——
7Q3LHuman 17S U2 snrnp 5' domainelectron microscopyB——
7Q4OSubstrate-bound A-like U2 snRNPelectron microscopyB—6 (best 0.70)
7Q4OSubstrate-bound a-like U2 snrnpelectron microscopyB——
7Q4PU2 snRNP after ATP-dependent remodellingelectron microscopyB—8 (best 0.77)
7Q4PU2 snrnp after ATP-dependent remodellingelectron microscopyB——
7VPXThe cryo-EM structure of the human pre-A complexelectron microscopy2—4 (best 0.82)
8CH6Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius…electron microscopyE—1 (best 0.85)
8H6ECryo-EM structure of human exon-defined spliceosome in the late pre-B state.electron microscopy2H——
8H6KCryo-EM structure of human exon-defined spliceosome in the mature B state.electron microscopy2H——
8HK1The cryo-EM structure of human pre-17S U2 snRNPelectron microscopy2—3 (best 0.83)
8I0UThe cryo-EM structure of human Bact-IV complexelectron microscopy2——
8I0VThe cryo-EM structure of human post-Bact complexelectron microscopy2—1 (best 0.81)
8QZSCryo-EM structure of the cross-exon B-like complexelectron microscopyB2——
8R08Cryo-EM structure of the cross-exon pre-B+AMPPNP complexelectron microscopyB2—1 (best 0.86)
8R09Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complexelectron microscopyB2—2 (best 0.85)
8R0BCryo-EM structure of the cross-exon pre-B+ATP complexelectron microscopyB2—2 (best 0.85)
8RM5Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complexelectron microscopyB2——
Q13435AlphaFold monomer V2.0 prediction for splicing factor 3B subunit 2 (Q13435)———

Elsewhere

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