UniProt Q13405
39S ribosomal protein L49, mitochondrial (Q13405)
39S ribosomal protein L49, mitochondrial (UniProt Q13405): 32 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q13405
- Protein
- 39S ribosomal protein L49, mitochondrial
- Experimental structures
- 32
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 7 records with a druggable one
Structures
33 records of Q13405 in the MolNFT archive: 32 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J7Y | Structure of the large ribosomal subunit from human mitochondria | electron microscopy | g | — | — |
| 3J7Y | Structure of the large ribosomal subunit from human mitochondria | electron microscopy | g | — | — |
| 3J9M | Structure of the human mitochondrial ribosome (class 1) | electron microscopy | g | — | — |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | g | MG | — |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | g | MG | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | g | MG | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | g | MG | — |
| 6I9R | Large subunit of the human mitochondrial ribosome in complex with Virginiamycin M and Quinupristin | electron microscopy | g | MG | — |
| 6NU2 | Structural insights into unique features of the human mitochondrial ribosome recycling | electron microscopy | g | MG | — |
| 6ZS9 | Human mitochondrial ribosome in complex with ribosome recycling factor | electron microscopy | g | MG | — |
| 6ZSB | Human mitochondrial ribosome in complex with mRNA and P-site tRNA | electron microscopy | g | MG | — |
| 6ZSC | Human mitochondrial ribosome in complex with E-site tRNA | electron microscopy | g | MG | 1 (best 0.85) |
| 7L20 | Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt. | electron microscopy | g | MG | — |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | g | MG | 1 (best 0.82) |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | g | MG | — |
| 7OF4 | Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC… | electron microscopy | g | MG | — |
| 7OF5 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | g | MG | 2 (best 0.88) |
| 7OI6 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 1 | electron microscopy | g | MG | — |
| 7OI7 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2 | electron microscopy | g | MG | — |
| 7OI8 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A | electron microscopy | g | MG | — |
| 7OI9 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B | electron microscopy | g | MG | — |
| 7OIA | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C | electron microscopy | g | MG | — |
| 7OIB | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D | electron microscopy | g | MG | — |
| 7OIC | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4 | electron microscopy | g | MG | 2 (best 0.82) |
| 7OIE | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B | electron microscopy | g | — | — |
| 7PD3 | Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and… | electron microscopy | g | MG | — |
| 7QH6 | Cryo-EM structure of the human mtlsu assembly intermediate upon MRM2 depletion - class 1 | electron microscopy | g | — | — |
| 7QH7 | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 4 | electron microscopy | g | — | — |
| 7QH7 | Cryo-EM structure of the human mtlsu assembly intermediate upon MRM2 depletion - class 4 | electron microscopy | g | — | — |
| 8K2A | Cryo-EM structure of the human 55S mitoribosome with Tigecycline | electron microscopy | Lw | MG | 1 (best 0.87) |
| 8OIR | 55S human mitochondrial ribosome with mtRF1 and P-site tRNA | electron microscopy | Bx | MG | 1 (best 0.88) |
| 8OIT | 39S human mitochondrial large ribosomal subunit with mtRF1 and P-site tRNA | electron microscopy | Bx | MG | 2 (best 0.87) |
| Q13405 | AlphaFold monomer V2.0 prediction for 39S ribosomal protein L49, mitochondrial (Q13405) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 25 records
Experiment against prediction
- 5OOM chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.80 Å
- 5OOM chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.80 Å
- 7OF0 chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.79 Å
- 7OF0 chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.79 Å
- 7OF5 chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.80 Å
- 7QH7 chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.79 Å
- 7QH7 chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.79 Å
- 7OIB chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.83 Å
- 7OI9 chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.83 Å
- 5OOL chain g against the predicted model Q13405: TM-score 0.97, RMSD 0.83 Å
Elsewhere
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