UniProt Q13362
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Q13362)
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (UniProt Q13362): 31 experimental structures and 1 predicted model on GenesisL1, 33 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q13362
- Protein
- Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
- Experimental structures
- 31
- Predicted models
- 1
- Pockets
- 33 · 4 records with a druggable one
Structures
32 records of Q13362 in the MolNFT archive: 31 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2IAE | Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme. | x-ray diffraction | B, E | — | — |
| 2IAE | Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme. | x-ray diffraction | B, E | — | — |
| 2JAK | Human PP2A regulatory subunit B56g | x-ray diffraction | A | — | — |
| 2JAK | Human PP2A regulatory subunit B56G | x-ray diffraction | A | — | — |
| 2NPP | Structure of the Protein Phosphatase 2A Holoenzyme | x-ray diffraction | B, E | — | — |
| 2NPP | Structure of the protein phosphatase 2A holoenzyme | x-ray diffraction | B, E | — | — |
| 2NYL | Crystal structure of Protein Phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl… | x-ray diffraction | B, E | — | — |
| 2NYL | Crystal structure of protein phosphatase 2A (PP2A) holoenzyme with the catalytic subunit carboxyl… | x-ray diffraction | B, E | — | — |
| 2NYM | Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit | x-ray diffraction | B, E | — | — |
| 2NYM | Crystal structure of protein phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit | x-ray diffraction | B, E | — | — |
| 3FGA | Structural Basis of PP2A and Sgo interaction | x-ray diffraction | B | — | — |
| 3FGA | Structural basis of PP2A and sgo interaction | x-ray diffraction | B | — | — |
| 5JJA | Crystal structure of a PP2A B56gamma/BubR1 complex | x-ray diffraction | A, B | — | 4 (best 0.66) |
| 5JJA | Crystal structure of a PP2A B56GAMMA/BUBR1 complex | x-ray diffraction | A, B | — | — |
| 5K6S | The structure of the PP2A B56 subunit BubR1 complex | x-ray diffraction | A | — | — |
| 5K6S | The structure of the PP2A B56 subunit BUBR1 complex | x-ray diffraction | A | — | — |
| 5SW9 | The structure of the PP2A B56 subunit RepoMan complex | x-ray diffraction | A | — | — |
| 5SW9 | The structure of the PP2A B56 subunit repoman complex | x-ray diffraction | A | — | — |
| 5SWF | The structure of the PP2A B56 subunit double phosphorylated BubR1 complex | x-ray diffraction | A | — | — |
| 5SWF | The structure of the PP2A B56 subunit double phosphorylated BUBR1 complex | x-ray diffraction | A | — | — |
| 6OYL | The structure of the PP2A B56 subunit KIF4A complex | x-ray diffraction | A | — | 3 (best 0.60) |
| 6OYL | The structure of the PP2A B56 subunit KIF4A complex | x-ray diffraction | A | — | — |
| 6VOY | Cryo-EM structure of HTLV-1 instasome | electron microscopy | E, F | — | 11 (best 0.86) |
| 6VOY | Cryo-EM structure of HTLV-1 instasome | electron microscopy | E, F | — | — |
| 6VRO | The structure of the PP2A B56 subunit AIM1 complex | x-ray diffraction | A | — | 2 (best 0.44) |
| 6VRO | The structure of the PP2A B56 subunit AIM1 complex | x-ray diffraction | A | — | — |
| 7OUF | Structure of the STLV intasome:B56 complex bound to the strand-transfer inhibitor XZ450 | electron microscopy | F, C | — | 13 (best 0.81) |
| 7OUF | Structure of the stlv INTASOME:B56 complex bound to the strand- transfer inhibitor XZ450 | electron microscopy | F, C | — | — |
| 7OUG | Stlv-1 INTASOME:B56 in complex with the strand-transfer inhibitor raltegravir | electron microscopy | F, C | — | — |
| 7PEL | Cryoem structure of simian T-cell lymphotropic virus intasome in complex with PP2A regulatory… | electron microscopy | C, F | — | — |
| 7SOY | The structure of the PP2A-B56GAMMA1 holoenzyme-pme-1 complex | electron microscopy | B | — | — |
| Q13362 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein phosphatase 2A 56 kda regulatory… | predicted | A | — | — |
Experiment against prediction
- 5JJA chain A against the predicted model Q13362: TM-score 0.98, RMSD 0.98 Å
- 5JJA chain A against the predicted model Q13362: TM-score 0.98, RMSD 0.98 Å
- 2IAE chain E against the predicted model Q13362: TM-score 0.98, RMSD 1.09 Å
- 2IAE chain E against the predicted model Q13362: TM-score 0.98, RMSD 1.09 Å
- 5JJA chain B against the predicted model Q13362: TM-score 0.98, RMSD 1.07 Å
- 5JJA chain B against the predicted model Q13362: TM-score 0.98, RMSD 1.07 Å
- 2IAE chain B against the predicted model Q13362: TM-score 0.97, RMSD 1.13 Å
- 2IAE chain B against the predicted model Q13362: TM-score 0.97, RMSD 1.13 Å
- 7SOY chain B against the predicted model Q13362: TM-score 0.97, RMSD 1.25 Å
- 7OUG chain F against the predicted model Q13362: TM-score 0.97, RMSD 1.14 Å
Elsewhere
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