UniProt Q13216
DNA excision repair protein ERCC-8 (Q13216)
DNA excision repair protein ERCC-8 (UniProt Q13216): 22 experimental structures and 1 predicted model on GenesisL1, 75 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13216
- Protein
- DNA excision repair protein ERCC-8
- Experimental structures
- 22
- Predicted models
- 1
- Pockets
- 75 · 14 records with a druggable one
Structures
23 records of Q13216 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4A11 | Structure of the hsDDB1-hsCSA complex | x-ray diffraction | B | — | — |
| 4A11 | Structure of the HSDDB1-hscsa complex | x-ray diffraction | B | — | — |
| 6FCV | Structure of the human DDB1-CSA complex | x-ray diffraction | B | — | 6 (best 0.85) |
| 6FCV | Structure of the human DDB1-csa complex | x-ray diffraction | B | — | — |
| 7OO3 | Pol II-CSB-CSA-DDB1-UVSSA (Structure1) | electron microscopy | a | — | 3 (best 0.86) |
| 7OO3 | Pol II-csb-csa-DDB1-uvssa (STRUCTURE1) | electron microscopy | a | — | — |
| 7OOB | Pol II-CSB-CSA-DDB1-UVSSA-ADPBeF3 (Structure2) | electron microscopy | a | — | 3 (best 0.83) |
| 7OOB | Pol II-csb-csa-DDB1-uvssa-ADPBEF3 (STRUCTURE2) | electron microscopy | a | — | — |
| 7OOP | Pol II-CSB-CSA-DDB1-UVSSA-PAF-SPT6 (Structure 3) | electron microscopy | a | — | 3 (best 0.85) |
| 7OOP | Pol II-csb-csa-DDB1-uvssa-paf-SPT6 (structure 3) | electron microscopy | a | — | — |
| 7OPC | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 4) | electron microscopy | a | — | 4 (best 0.83) |
| 7OPC | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 4) | electron microscopy | a | — | — |
| 7OPD | Pol II-CSB-CRL4CSA-UVSSA-SPT6-PAF (Structure 5) | electron microscopy | a | — | 4 (best 0.85) |
| 7OPD | Pol II-csb-CRL4CSA-uvssa-SPT6-paf (structure 5) | electron microscopy | a | — | — |
| 8B3D | Structure of the Pol II-TCR-ELOF1 complex. | electron microscopy | a | — | 5 (best 0.85) |
| 8B3F | Pol II-CSB-CSA-DDB1-ELOF1 | electron microscopy | a | — | 5 (best 0.85) |
| 8B3G | C(N)RL4CSA-UVSSA-E2-ubiquitin complex. | electron microscopy | a | — | 8 (best 0.83) |
| 8B3I | CRL4CSA-E2-Ub (state 2) | electron microscopy | a | — | 7 (best 0.85) |
| 8QH5 | CryoEM structure of UVSSA(VHS)-CSA-DDB1-DDA1 | electron microscopy | A | — | 9 (best 0.87) |
| 9BZ0 | Structure of an STK19-containing TC-NER complex | electron microscopy | a | — | 7 (best 0.83) |
| 9ER2 | PolII-TCR-STK19 structure. | electron microscopy | a | — | 6 (best 0.83) |
| 9FD2 | Structure of Pol II-TC-NER-STK19 complex | electron microscopy | a | — | 5 (best 0.85) |
| Q13216 | AlphaFold monomer V2.0 prediction for DNA excision repair protein ercc-8 (Q13216) | predicted | A | — | — |
Experiment against prediction
- 6FCV chain B against the predicted model Q13216: TM-score 1.00, RMSD 0.36 Å
- 6FCV chain B against the predicted model Q13216: TM-score 1.00, RMSD 0.36 Å
- 4A11 chain B against the predicted model Q13216: TM-score 1.00, RMSD 0.49 Å
- 4A11 chain B against the predicted model Q13216: TM-score 1.00, RMSD 0.49 Å
- 7OOP chain a against the predicted model Q13216: TM-score 0.99, RMSD 0.72 Å
- 7OOP chain a against the predicted model Q13216: TM-score 0.99, RMSD 0.72 Å
- 7OPD chain a against the predicted model Q13216: TM-score 0.99, RMSD 0.72 Å
- 7OPD chain a against the predicted model Q13216: TM-score 0.99, RMSD 0.72 Å
- 7OPC chain a against the predicted model Q13216: TM-score 0.99, RMSD 0.72 Å
- 7OPC chain a against the predicted model Q13216: TM-score 0.99, RMSD 0.72 Å
Elsewhere
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