UniProt Q13111
Chromatin assembly factor 1 subunit A (Q13111)
Chromatin assembly factor 1 subunit A (UniProt Q13111): 6 experimental structures and 1 predicted model on GenesisL1, 49 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q13111
- Protein
- Chromatin assembly factor 1 subunit A
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 49 · 6 records with a druggable one
Structures
7 records of Q13111 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7Y5L | Crystal structure of human CAF-1 core complex in spacegroup C2 | x-ray diffraction | A, D | — | 14 (best 0.86) |
| 7Y5O | Crystal structure of human CAF-1 core complex in spacegroup P21 | x-ray diffraction | A, D | — | 16 (best 0.86) |
| 7Y5V | Cryo-EM structure of the dimeric human CAF1LC-H3-H4 complex | electron microscopy | A, F | — | 7 (best 0.69) |
| 7Y60 | Cryo-EM structure of human CAF1LC bound right-handed Di-tetrasome | electron microscopy | K | — | 3 (best 0.79) |
| 7Y61 | Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome | electron microscopy | K, M | — | 2 (best 0.67) |
| 8IQF | Cryo-EM structure of the dimeric human CAF1-H3-H4 complex | electron microscopy | A, F | — | 7 (best 0.70) |
| Q13111 | AlphaFold monomer V2.0 prediction for chromatin assembly factor 1 subunit a (Q13111) | predicted | A | — | — |
Experiment against prediction
- 7Y5L chain A against the predicted model Q13111: TM-score 0.38, RMSD 5.18 Å
- 7Y5L chain D against the predicted model Q13111: TM-score 0.38, RMSD 5.09 Å
- 7Y5O chain A against the predicted model Q13111: TM-score 0.38, RMSD 5.15 Å
- 7Y5O chain D against the predicted model Q13111: TM-score 0.38, RMSD 4.87 Å
- 8IQF chain F against the predicted model Q13111: TM-score 0.32, RMSD 3.52 Å
- 8IQF chain A against the predicted model Q13111: TM-score 0.32, RMSD 3.53 Å
- 7Y5V chain A against the predicted model Q13111: TM-score 0.32, RMSD 3.71 Å
- 7Y5V chain F against the predicted model Q13111: TM-score 0.32, RMSD 3.52 Å
- 7Y61 chain M against the predicted model Q13111: TM-score 0.26, RMSD 2.51 Å
- 7Y61 chain K against the predicted model Q13111: TM-score 0.22, RMSD 1.89 Å
Elsewhere
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