UniProt Q12929
Epidermal growth factor receptor kinase substrate 8 (Q12929)
Epidermal growth factor receptor kinase substrate 8 (UniProt Q12929): 4 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12929
- Protein
- Epidermal growth factor receptor kinase substrate 8
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of Q12929 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2E8M | Solution structure of the C-terminal SAM-domain of epidermal growth receptor pathway substrate 8 | solution nmr | A | — | — |
| 2E8M | Solution structure of the C-terminal SAM-domain of epidermal growth receptor pathway substrate 8 | solution nmr | A | — | — |
| 7TZK | EPS8 SH3 Domain with NleH1 PxxDY Motif | x-ray diffraction | A, B | — | 1 (best 0.40) |
| 7TZK | EPS8 SH3 domain with NLEH1 pxxdy motif | x-ray diffraction | A, B | — | — |
| Q12929 | AlphaFold monomer V2.0 prediction for epidermal growth factor receptor kinase substrate 8 (Q12929) | predicted | A | — | — |
Experiment against prediction
- 7TZK chain A against the predicted model Q12929: TM-score 0.91, RMSD 1.48 Å
- 7TZK chain A against the predicted model Q12929: TM-score 0.91, RMSD 1.48 Å
- 7TZK chain B against the predicted model Q12929: TM-score 0.91, RMSD 1.50 Å
- 7TZK chain B against the predicted model Q12929: TM-score 0.91, RMSD 1.50 Å
- 2E8M chain A against the predicted model Q12929: TM-score 0.69, RMSD 1.93 Å
- 2E8M chain A against the predicted model Q12929: TM-score 0.69, RMSD 1.93 Å
Elsewhere
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