UniProt Q12874
Splicing factor 3A subunit 3 (Q12874)
Splicing factor 3A subunit 3 (UniProt Q12874): 48 experimental structures on GenesisL1, 1 ligand bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q12874
- Protein
- Splicing factor 3A subunit 3
- Experimental structures
- 48
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 19 · 8 records with a druggable one
Structures
48 records of Q12874 in the MolNFT archive: 48 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2DT7 | Solution structure of the second SURP domain of human splicing factor SF3a120 in complex with a… | solution nmr | A | — | — |
| 2DT7 | Solution structure of the second surp domain of human splicing factor SF3A120 in complex with a… | solution nmr | A | — | — |
| 5Z56 | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | electron microscopy | w | — | — |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | electron microscopy | u | — | — |
| 5Z58 | Cryo-EM structure of a human activated spliceosome (early bact) at 4.9 ångström. | electron microscopy | w | — | — |
| 6AH0 | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | electron microscopy | w | — | — |
| 6AH0 | The cryo-EM structure of the precusor of human pre-catalytic spliceosome (pre-B complex) | electron microscopy | w | — | — |
| 6AHD | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | electron microscopy | w | — | — |
| 6FF7 | human Bact spliceosome core structure | electron microscopy | 9 | ZN | — |
| 6FF7 | Human bact spliceosome core structure | electron microscopy | 9 | ZN | — |
| 6QX9 | Structure of a human fully-assembled precatalytic spliceosome (pre-B complex). | electron microscopy | A3 | — | 1 (best 0.78) |
| 6Y50 | 5'domain of human 17S U2 snRNP | electron microscopy | 9 | — | — |
| 6Y50 | 5'DOMAIN of human 17S U2 snrnp | electron microscopy | 9 | — | — |
| 6Y53 | human 17S U2 snRNP low resolution part | electron microscopy | 9 | — | — |
| 6Y53 | Human 17S U2 snrnp low resolution part | electron microscopy | 9 | — | — |
| 6Y5Q | Human 17S U2 snrnp | electron microscopy | 9 | — | — |
| 7ABG | Human pre-Bact-1 spliceosome | electron microscopy | 4 | — | — |
| 7ABH | Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion) | electron microscopy | 4 | — | — |
| 7ABH | Human pre-bact-2 spliceosome (SF3B/U2 snrnp portion) | electron microscopy | 4 | — | — |
| 7ABI | Human pre-Bact-2 spliceosome | electron microscopy | 4 | — | — |
| 7ABI | Human pre-bact-2 spliceosome | electron microscopy | 4 | — | — |
| 7EVO | The cryo-EM structure of the human 17S U2 snRNP | electron microscopy | C | ZN | — |
| 7EVO | The cryo-EM structure of the human 17S U2 snrnp | electron microscopy | C | ZN | — |
| 7ONB | Structure of the U2 5' module of the A3'-ssa complex | electron microscopy | N | ZN | — |
| 7Q3L | Human 17S U2 snRNP 5' domain | electron microscopy | 9 | ZN | 4 (best 0.80) |
| 7Q3L | Human 17S U2 snrnp 5' domain | electron microscopy | 9 | ZN | — |
| 7Q4O | Substrate-bound A-like U2 snRNP | electron microscopy | 9 | ZN | 4 (best 0.70) |
| 7Q4O | Substrate-bound a-like U2 snrnp | electron microscopy | 9 | ZN | — |
| 7Q4P | U2 snRNP after ATP-dependent remodelling | electron microscopy | 9 | ZN | 5 (best 0.77) |
| 7Q4P | U2 snrnp after ATP-dependent remodelling | electron microscopy | 9 | ZN | — |
| 7VPX | The cryo-EM structure of the human pre-A complex | electron microscopy | C | ZN | 2 (best 0.80) |
| 8CH6 | Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius… | electron microscopy | J | ZN | 1 (best 0.84) |
| 8H6E | Cryo-EM structure of human exon-defined spliceosome in the late pre-B state. | electron microscopy | 2F | — | — |
| 8H6J | Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state. | electron microscopy | 2F | — | — |
| 8H6K | Cryo-EM structure of human exon-defined spliceosome in the mature B state. | electron microscopy | 2F | — | — |
| 8H6L | Cryo-EM structure of human exon-defined spliceosome in the early B state. | electron microscopy | 2F | — | — |
| 8HK1 | The cryo-EM structure of human pre-17S U2 snRNP | electron microscopy | C | ZN | 1 (best 0.69) |
| 8I0P | The cryo-EM structure of human pre-Bact complex | electron microscopy | w | — | — |
| 8I0T | The cryo-EM structure of human Bact-III complex | electron microscopy | w | — | — |
| 8I0U | The cryo-EM structure of human Bact-IV complex | electron microscopy | w | — | — |
| 8QO9 | Cryo-EM structure of a human spliceosomal B complex protomer | electron microscopy | 9, H | — | — |
| 8QZS | Cryo-EM structure of the cross-exon B-like complex | electron microscopy | 9 | — | — |
| 8R08 | Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | electron microscopy | 9 | — | 1 (best 0.82) |
| 8R09 | Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex | electron microscopy | 9 | — | — |
| 8R0A | Cryo-EM structure of the cross-exon pre-B+5'ss complex | electron microscopy | 9 | — | — |
| 8R0B | Cryo-EM structure of the cross-exon pre-B+ATP complex | electron microscopy | 9 | — | — |
| 8RM5 | Cryo-EM structure of the cross-exon pre-B+5'ssLNG+ATPyS complex | electron microscopy | 9 | — | — |
| Q12874 | AlphaFold monomer V2.0 prediction for splicing factor 3A subunit 3 (Q12874) | — | — | — |
Ligands
- ZN · Zinc ion · in 14 records
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.