UniProt Q12748
Inner kinetochore subunit CTF3 (Q12748)
Inner kinetochore subunit CTF3 (UniProt Q12748): 16 experimental structures and 1 predicted model on GenesisL1, 61 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12748
- Protein
- Inner kinetochore subunit CTF3
- Experimental structures
- 16
- Predicted models
- 1
- Pockets
- 61 · 8 records with a druggable one
Structures
17 records of Q12748 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6NUW | Yeast CTF19 complex | electron microscopy | H, Y | — | — |
| 6OUA | Cryo-EM structure of the yeast Ctf3 complex | electron microscopy | I | — | 10 (best 0.60) |
| 6OUA | Cryo-EM structure of the yeast CTF3 complex | electron microscopy | I | — | — |
| 6QLD | Structure of inner kinetochore CCAN-Cenp-A complex | electron microscopy | I | — | — |
| 6QLD | Structure of inner kinetochore ccan-cenp-a complex | electron microscopy | I | — | — |
| 6QLE | Structure of inner kinetochore CCAN complex | electron microscopy | I | — | 5 (best 0.71) |
| 6QLE | Structure of inner kinetochore ccan complex | electron microscopy | I | — | — |
| 6WUC | The yeast Ctf3 complex with Cnn1-Wip1 | electron microscopy | I | — | 14 (best 0.81) |
| 6WUC | The yeast CTF3 complex with CNN1-WIP1 | electron microscopy | I | — | — |
| 6YPC | Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9… | x-ray diffraction | I | — | 5 (best 0.60) |
| 6YPC | Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9… | x-ray diffraction | I | — | — |
| 7L7Q | Ctf3c with Ulp2-KIM | electron microscopy | I | — | 10 (best 0.65) |
| 7L7Q | CTF3C with ULP2-kim | electron microscopy | I | — | — |
| 8OVW | Cryo-EM structure of CBF1-CCAN bound topologically to centromeric DNA | electron microscopy | I | — | 6 (best 0.78) |
| 8OW0 | Cryo-EM structure of CBF1-CCAN bound topologically to a centromeric CENP-A nucleosome | electron microscopy | I | — | 7 (best 0.78) |
| 8OW1 | Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome. | electron microscopy | I, II | — | 4 (best 0.81) |
| Q12748 | AlphaFold monomer V2.0 prediction for inner kinetochore subunit CTF3 (Q12748) | predicted | A | — | — |
Experiment against prediction
- 6YPC chain I against the predicted model Q12748: TM-score 1.00, RMSD 0.39 Å
- 6YPC chain I against the predicted model Q12748: TM-score 1.00, RMSD 0.39 Å
- 6QLE chain I against the predicted model Q12748: TM-score 0.97, RMSD 1.37 Å
- 6QLE chain I against the predicted model Q12748: TM-score 0.97, RMSD 1.37 Å
- 6QLD chain I against the predicted model Q12748: TM-score 0.97, RMSD 1.39 Å
- 6QLD chain I against the predicted model Q12748: TM-score 0.97, RMSD 1.39 Å
- 7L7Q chain I against the predicted model Q12748: TM-score 0.95, RMSD 1.86 Å
- 7L7Q chain I against the predicted model Q12748: TM-score 0.95, RMSD 1.86 Å
- 6OUA chain I against the predicted model Q12748: TM-score 0.94, RMSD 1.69 Å
- 6OUA chain I against the predicted model Q12748: TM-score 0.94, RMSD 1.69 Å
Elsewhere
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