UniProt Q12509
Actin-like protein ARP6 (Q12509)
Actin-like protein ARP6 (UniProt Q12509): 9 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12509
- Protein
- Actin-like protein ARP6
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 17 · 7 records with a druggable one
Structures
10 records of Q12509 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GEJ | Chromatin remodeller-nucleosome complex at 3.6 A resolution. | electron microscopy | R | ADP, BEF, MG | 2 (best 0.83) |
| 6GEJ | Chromatin remodeller-nucleosome complex at 3.6 a resolution. | electron microscopy | R | ADP, BEF | — |
| 6GEN | Chromatin remodeller-nucleosome complex at 4.5 A resolution. | electron microscopy | R | ADP, BEF, MG | 2 (best 0.82) |
| 6GEN | Chromatin remodeller-nucleosome complex at 4.5 a resolution. | electron microscopy | R | ADP, BEF | — |
| 8QKU | SWR1-nucleosome complex in configuration 1 | electron microscopy | R | ADP, BEF, MG | 3 (best 0.87) |
| 8QKV | SWR1-nucleosome complex in configuration 2 | electron microscopy | R | ADP, BEF, MG | 3 (best 0.88) |
| 8QZ0 | SWR1-hexasome-dimer complex | electron microscopy | R | ADP, BEF, MG | 3 (best 0.90) |
| 9B1E | Cryo-EM structure of native SWR1 bound to nucleosome (composite structure) | electron microscopy | C | ADP, BEF, MG | 2 (best 0.82) |
| 9FBW | SWR1 lacking Swc5 subunit in complex with hexasome | electron microscopy | R | ADP, BEF, MG | 2 (best 0.88) |
| Q12509 | AlphaFold monomer V2.0 prediction for actin-like protein ARP6 (Q12509) | predicted | A | — | — |
Ligands
Experiment against prediction
- 9B1E chain C against the predicted model Q12509: TM-score 0.98, RMSD 0.99 Å
- 8QKU chain R against the predicted model Q12509: TM-score 0.97, RMSD 1.25 Å
- 6GEJ chain R against the predicted model Q12509: TM-score 0.97, RMSD 1.30 Å
- 6GEJ chain R against the predicted model Q12509: TM-score 0.97, RMSD 1.30 Å
- 6GEN chain R against the predicted model Q12509: TM-score 0.97, RMSD 1.31 Å
- 6GEN chain R against the predicted model Q12509: TM-score 0.97, RMSD 1.31 Å
- 8QKV chain R against the predicted model Q12509: TM-score 0.97, RMSD 1.39 Å
- 9FBW chain R against the predicted model Q12509: TM-score 0.94, RMSD 1.86 Å
- 8QZ0 chain R against the predicted model Q12509: TM-score 0.94, RMSD 2.00 Å
Elsewhere
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