UniProt Q12440
Anaphase-promoting complex subunit 2 (Q12440)
Anaphase-promoting complex subunit 2 (UniProt Q12440): 6 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12440
- Protein
- Anaphase-promoting complex subunit 2
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 2 · 1 record with a druggable one
Structures
7 records of Q12440 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1LDD | Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF Ubiquitin Ligase Complex | x-ray diffraction | A, B, C, D | — | — |
| 1LDD | Structure of the CUL1-RBX1-SKP1-F BOXSKP2 scf ubiquitin ligase complex | x-ray diffraction | A, B, C, D | — | — |
| 8A3T | S. cerevisiae APC/C-Cdh1 complex | electron microscopy | T | — | 2 (best 0.77) |
| 8A3T | S. cerevisiae APC/C-CDH1 complex | electron microscopy | T | — | — |
| 8A5Y | S. cerevisiae apo unphosphorylated APC/C | electron microscopy | T | — | — |
| 8A61 | S. cerevisiae apo phosphorylated APC/C | electron microscopy | T | — | — |
| Q12440 | AlphaFold monomer V2.0 prediction for anaphase-promoting complex subunit 2 (Q12440) | predicted | A | — | — |
Experiment against prediction
- 1LDD chain C against the predicted model Q12440: TM-score 0.97, RMSD 0.83 Å
- 1LDD chain C against the predicted model Q12440: TM-score 0.97, RMSD 0.83 Å
- 1LDD chain B against the predicted model Q12440: TM-score 0.96, RMSD 0.83 Å
- 1LDD chain B against the predicted model Q12440: TM-score 0.96, RMSD 0.83 Å
- 1LDD chain A against the predicted model Q12440: TM-score 0.96, RMSD 0.84 Å
- 1LDD chain A against the predicted model Q12440: TM-score 0.96, RMSD 0.84 Å
- 1LDD chain D against the predicted model Q12440: TM-score 0.96, RMSD 0.84 Å
- 1LDD chain D against the predicted model Q12440: TM-score 0.96, RMSD 0.84 Å
- 8A3T chain T against the predicted model Q12440: TM-score 0.95, RMSD 1.97 Å
- 8A3T chain T against the predicted model Q12440: TM-score 0.95, RMSD 1.97 Å
Elsewhere
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