UniProt Q12262

Inner kinetochore subunit MCM16 (Q12262)

Inner kinetochore subunit MCM16 (UniProt Q12262): 7 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q12262
Protein: Inner kinetochore subunit MCM16
Experimental structures: 7
Predicted models: 1
Pockets: 3 · 1 record with a druggable one

Structures

8 records of Q12262 in the MolNFT archive: 7 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6OUA	Cryo-EM structure of the yeast CTF3 complex	electron microscopy	H	—	—
6QLD	Structure of inner kinetochore CCAN-Cenp-A complex	electron microscopy	H	—	—
6QLD	Structure of inner kinetochore ccan-cenp-a complex	electron microscopy	H	—	—
6WUC	The yeast CTF3 complex with CNN1-WIP1	electron microscopy	H	—	—
6YPC	Crystal structure of the kinetochore subunits H/I/K/T/W penta-complex from S. cerevisiae at 2.9…	x-ray diffraction	H	—	—
7L7Q	CTF3C with ULP2-kim	electron microscopy	H	—	—
8OW1	Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome.	electron microscopy	H, HH	—	3 (best 0.81)
Q12262	AlphaFold monomer V2.0 prediction for inner kinetochore subunit MCM16 (Q12262)	predicted	A	—	—

Experiment against prediction

6QLD chain H against the predicted model Q12262: TM-score 0.95, RMSD 0.95 Å
6QLD chain H against the predicted model Q12262: TM-score 0.95, RMSD 0.95 Å
7L7Q chain H against the predicted model Q12262: TM-score 0.94, RMSD 1.09 Å
6OUA chain H against the predicted model Q12262: TM-score 0.88, RMSD 1.53 Å
6YPC chain H against the predicted model Q12262: TM-score 0.88, RMSD 0.81 Å
6WUC chain H against the predicted model Q12262: TM-score 0.74, RMSD 1.87 Å
8OW1 chain HH against the predicted model Q12262: TM-score 0.72, RMSD 1.96 Å
8OW1 chain H against the predicted model Q12262: TM-score 0.68, RMSD 2.17 Å

Elsewhere

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