UniProt Q12136
Something about silencing protein 10 (Q12136)
Something about silencing protein 10 (UniProt Q12136): 11 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12136
- Protein
- Something about silencing protein 10
- Experimental structures
- 11
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
12 records of Q12136 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5WLC | The complete structure of the small subunit processome | electron microscopy | NB | — | — |
| 6LQP | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A) | electron microscopy | 5H | — | — |
| 6LQQ | Cryo-EM structure of 90S small subunit preribosomes in transition states (State B) | electron microscopy | 5H | — | — |
| 6LQR | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C) | electron microscopy | 5H | — | — |
| 6LQS | Cryo-EM structure of 90S small subunit preribosomes in transition states (State D) | electron microscopy | 5H | — | — |
| 6LQT | Cryo-EM structure of 90S small subunit preribosomes in transition states (State E) | electron microscopy | 5H | — | — |
| 6LQU | Cryo-EM structure of 90S small subunit preribosomes in transition states (State A1) | electron microscopy | 5H | — | — |
| 6LQV | Cryo-EM structure of 90S small subunit preribosomes in transition states (State C1) | electron microscopy | 5H | — | — |
| 6ZQE | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | electron microscopy | UC | — | 6 (best 0.85) |
| 7AJT | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | electron microscopy | UC | — | 2 (best 0.86) |
| 7WTL | Cryo-EM structure of a yeast pre-40S ribosomal subunit - State Dis-D | electron microscopy | UC | — | — |
| Q12136 | AlphaFold monomer V2.0 prediction for something about silencing protein 10 (Q12136) | predicted | A | — | 1 (best 0.37) |
Experiment against prediction
- 6LQQ chain 5H against the predicted model Q12136: TM-score 0.92, RMSD 0.90 Å
- 6LQR chain 5H against the predicted model Q12136: TM-score 0.92, RMSD 0.90 Å
- 6LQV chain 5H against the predicted model Q12136: TM-score 0.92, RMSD 0.90 Å
- 6LQS chain 5H against the predicted model Q12136: TM-score 0.89, RMSD 1.09 Å
- 6LQT chain 5H against the predicted model Q12136: TM-score 0.89, RMSD 1.09 Å
- 7WTL chain UC against the predicted model Q12136: TM-score 0.83, RMSD 1.08 Å
- 7AJT chain UC against the predicted model Q12136: TM-score 0.80, RMSD 1.71 Å
- 6ZQE chain UC against the predicted model Q12136: TM-score 0.77, RMSD 1.39 Å
- 6LQP chain 5H against the predicted model Q12136: TM-score 0.75, RMSD 1.75 Å
- 6LQU chain 5H against the predicted model Q12136: TM-score 0.75, RMSD 1.75 Å
Elsewhere
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