UniProt Q12083
DNA mismatch repair protein MLH3 (Q12083)
DNA mismatch repair protein MLH3 (UniProt Q12083): 7 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q12083
- Protein
- DNA mismatch repair protein MLH3
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 9 · 0 records with a druggable one
Structures
8 records of Q12083 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RMN | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | B | ZN | 3 (best 0.45) |
| 6RMN | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | B | ZN | — |
| 6SHX | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | B | ZN | 3 (best 0.49) |
| 6SHX | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | B | ZN | — |
| 6SNS | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | B | ZN | 3 (best 0.43) |
| 6SNS | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | B | ZN | — |
| 6SNV | DNA mismatch repair proteins MLH1 and MLH3 | x-ray diffraction | B, E | ZN | — |
| Q12083 | AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MLH3 (Q12083) | predicted | A | — | — |
Ligands
- ZN · Zinc ion · in 7 records
Experiment against prediction
- 6SNS chain B against the predicted model Q12083: TM-score 0.98, RMSD 1.02 Å
- 6SNS chain B against the predicted model Q12083: TM-score 0.98, RMSD 1.02 Å
- 6SHX chain B against the predicted model Q12083: TM-score 0.95, RMSD 1.50 Å
- 6SHX chain B against the predicted model Q12083: TM-score 0.95, RMSD 1.50 Å
- 6RMN chain B against the predicted model Q12083: TM-score 0.95, RMSD 1.51 Å
- 6RMN chain B against the predicted model Q12083: TM-score 0.95, RMSD 1.51 Å
- 6SNV chain B against the predicted model Q12083: TM-score 0.95, RMSD 1.50 Å
Elsewhere
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