UniProt Q10567
AP-1 complex subunit beta-1 (Q10567)
AP-1 complex subunit beta-1 (UniProt Q10567): 19 experimental structures and 1 predicted model on GenesisL1, 79 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q10567
- Protein
- AP-1 complex subunit beta-1
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 79 · 9 records with a druggable one
Structures
20 records of Q10567 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4HMY | Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1 | x-ray diffraction | B | — | — |
| 4HMY | Structural basis for recruitment and activation of the ap-1 clathrin adaptor complex by ARF1 | x-ray diffraction | B | — | — |
| 4P6Z | Crystal structure of the human BST2 cytoplasmic domain and the HIV-1 vpu cytoplasmic domain bound… | x-ray diffraction | B | — | — |
| 6CM9 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef closed trimer monomeric subunit | electron microscopy | B | — | — |
| 6CRI | Structure of the cargo bound AP-1:Arf1:tetherin-Nef stable closed trimer | electron microscopy | B, I, J | — | 14 (best 0.76) |
| 6CRI | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef stable closed trimer | electron microscopy | B, I, J | — | — |
| 6D83 | Structure of the cargo bound AP-1:Arf1:tetherin-Nef (L164A, L165A) dileucine mutant dimer monomeric… | electron microscopy | B | — | 11 (best 0.76) |
| 6D83 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef (L164A, L165A) dileucine mutant dimer monomeric… | electron microscopy | B | — | — |
| 6D84 | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef (L164A, L165A) dileucine mutant dimer | electron microscopy | B, F | — | — |
| 6DFF | Structure of the cargo bound AP-1:Arf1:tetherin-Nef monomer | electron microscopy | B | — | 12 (best 0.73) |
| 6DFF | Structure of the cargo bound ap-1:ARF1:TETHERIN-nef monomer | electron microscopy | B | — | — |
| 7R4H | phospho-STING binding to adaptor protein complex-1 | electron microscopy | B | — | 11 (best 0.73) |
| 8D4D | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide… | electron microscopy | B, A | — | 8 (best 0.70) |
| 8D4G | gamma-Arf1 mediated dimeric assembly of AP-1, Arf1, Nef complex within lattice on MHC-I lipopeptide… | electron microscopy | B, A | — | 7 (best 0.67) |
| 8D9R | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on… | electron microscopy | B, A, D, E, F, I | — | 2 (best 0.71) |
| 8D9S | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide membrane tubes, centered on beta-Arf1 | electron microscopy | B, A, D, E, F, I | — | 5 (best 0.71) |
| 8D9T | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on… | electron microscopy | B, A, D, E, F, I | — | — |
| 8D9U | AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated narrow membrane tubes, centered on… | electron microscopy | B, A, D, E, F, I | — | — |
| 8D9W | beta-Arf1 homodimeric interface within AP-1, Arf1, Nef, MHC-I lattice on narrow tubes | electron microscopy | B, A, D, E | — | 9 (best 0.67) |
| Q10567 | AlphaFold monomer V2.0 prediction for ap-1 complex subunit beta-1 (Q10567) | predicted | A | — | — |
Experiment against prediction
- 8D9W chain E against the predicted model Q10567: TM-score 0.96, RMSD 1.31 Å
- 8D9W chain B against the predicted model Q10567: TM-score 0.96, RMSD 1.26 Å
- 8D9W chain D against the predicted model Q10567: TM-score 0.95, RMSD 1.40 Å
- 8D9W chain A against the predicted model Q10567: TM-score 0.95, RMSD 1.41 Å
- 8D4D chain B against the predicted model Q10567: TM-score 0.95, RMSD 2.00 Å
- 8D4D chain A against the predicted model Q10567: TM-score 0.95, RMSD 2.00 Å
- 4P6Z chain B against the predicted model Q10567: TM-score 0.95, RMSD 2.01 Å
- 6CRI chain I against the predicted model Q10567: TM-score 0.95, RMSD 2.00 Å
- 6CRI chain I against the predicted model Q10567: TM-score 0.95, RMSD 2.00 Å
- 6CRI chain B against the predicted model Q10567: TM-score 0.95, RMSD 2.00 Å
Elsewhere
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